siRNA, Anti-APOBEC1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT01226WQ-2OMe)

The product SIRGT01226WQ-2OMe is a type of small interfering RNA (siRNA) that targets APOBEC1 gene and regulates the expression of gene. The siRNA interferes with the expression of APOBEC1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001304566.1; NM_001644.4; NM_005889.3
Alternative Names APOBEC-1; BEDP; CDAR1; HEPR
Related Diseases Immune Deficiency Disease
Purification HPLC
Target Gene
Gene ID 339
Uniprot ID P41238
Sub Cat Target Species Modification Scale  
SIRGT02226WQ-2F APOBEC1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03226WQ-2MOE APOBEC1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT01226WQ-RB APOBEC1 Human Ribo-modified Inquiry
SIRGT02226WQ-BB APOBEC1 Human Backbone-modified Inquiry

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