siRNA, Anti-APOC2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01229WQ-2OMe)

The product SIRGT01229WQ-2OMe is a type of small interfering RNA (siRNA) that targets APOC2 gene and regulates the expression of gene. The siRNA interferes with the expression of APOC2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000483.4
Alternative Names APO-CII; APOC-II
Related Diseases Apolipoprotein C-Ii Deficiency, Pancreatitis
Purification HPLC
Target Gene
Gene ID 344
Uniprot ID P02655
Sub Cat Target Species Modification Scale  
SIRGT02229WQ-2F APOC2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03229WQ-2MOE APOC2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04229WQ-LNA APOC2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01229WQ-RB APOC2 Human Ribo-modified Inquiry
SIRGT02229WQ-BB APOC2 Human Backbone-modified Inquiry

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