siRNA, Anti-AQP1, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT01241WQ-2OMe)

The product SIRGT01241WQ-2OMe is a type of small interfering RNA (siRNA) that targets AQP1 gene and regulates the expression of gene. The siRNA interferes with the expression of AQP1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001329872.1; NM_198098.3
Alternative Names AQP-CHIP; CHIP28; CO
Related Diseases Diabetes Insipidus, Nephrogenic
Purification HPLC
Target Gene
Gene ID 358
Uniprot ID P29972
Sub Cat Target Species Modification Scale  
SIRGT02241WQ-2F AQP1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT04241WQ-LNA AQP1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01241WQ-RB AQP1 Human Ribo-modified Inquiry
SIRGT02241WQ-BB AQP1 Human Backbone-modified Inquiry

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