siRNA, Anti-CCDC8, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46735WQ-2OMe)

The product SIRGT46735WQ-2OMe is a type of small interfering RNA (siRNA) that targets CCDC8 gene and regulates the expression of gene. The siRNA interferes with the expression of CCDC8 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_032040.4
Alternative Names 3M3; PPP1R20; p90
Related Diseases Three M Syndrome 3
Purification HPLC
Target Gene
Gene ID 83987
Uniprot ID Q9H0W5
Sub Cat Target Species Modification Scale  
SIRGT47735WQ-2F CCDC8 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48735WQ-2MOE CCDC8 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49735WQ-LNA CCDC8 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46735WQ-RB CCDC8 Human Ribo-modified Inquiry
SIRGT47735WQ-BB CCDC8 Human Backbone-modified Inquiry

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