siRNA, Anti-NCALD, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46736WQ-2OMe)

The product SIRGT46736WQ-2OMe is a type of small interfering RNA (siRNA) that targets NCALD gene and regulates the expression of gene. The siRNA interferes with the expression of NCALD gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001040624.1
Related Diseases Spinal Muscular Atrophy
Purification HPLC
Target Gene
Gene ID 83988
Uniprot ID P61601
Sub Cat Target Species Modification Scale  
SIRGT47736WQ-2F NCALD Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48736WQ-2MOE NCALD Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49736WQ-LNA NCALD Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46736WQ-RB NCALD Human Ribo-modified Inquiry
SIRGT47736WQ-BB NCALD Human Backbone-modified Inquiry

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