siRNA, Anti-TMEM107, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46907WQ-2OMe)

The product SIRGT46907WQ-2OMe is a type of small interfering RNA (siRNA) that targets TMEM107 gene and regulates the expression of gene. The siRNA interferes with the expression of TMEM107 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001351278.1
Alternative Names GRVS638; JBTS29; MKS13; PRO1268
Related Diseases Meckel Syndrome
Purification HPLC
Target Gene
Gene ID 84314
Uniprot ID Q6UX40
Sub Cat Target Species Modification Scale  
SIRGT47907WQ-2F TMEM107 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48907WQ-2MOE TMEM107 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49907WQ-LNA TMEM107 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46907WQ-RB TMEM107 Human Ribo-modified Inquiry
SIRGT47907WQ-BB TMEM107 Human Backbone-modified Inquiry

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