Creative Biolabs has been engaged in biological research for many years, and we have successfully supported numerous biological researchers from all over the world to advance their experiments with fair and unanimous praise.
H-Ficolin, also known as Ficolin-3, Hakata antigen, heat-resistant β-2 macro glycoprotein, is one of the lectins involved in innate immunity in human serum. Ficolin-3 recognizes acetyl groups and binds to acetylated carbohydrates on the surface of pathogens to activate the complement system in an antibody-independent manner. In addition, studies have also shown that Ficolin-3 interacts with specific polysaccharide or lipopolysaccharide components of certain pathogenic microorganisms. The Ficolin-3 component in serum can form a complex with MASP and its truncated protein. Using this property, Ficolin-3 can be purified from serum as a complex. Here, we briefly summarize the protocol for assessing the complement activation function of the ficolin-3-dependent lectin pathway, and provide simple technical references for your related research.
Ficolin-3-Pathway of Complement Analysis Protocol
Fig 1. The flow of ficolin-3-pathway of complement analysis protocol. (Creative Biolabs)
Complement-related research can be very complicated, and Creative Biolabs uses comprehensive professional knowledge and advanced technology platforms to wisely select and carry out any related tests for you, and provide accurate and reliable test results and final interpretations. With our extremely flexible service options, you can entrust us with the entire research project and validation work, freeing up your time for other important work. We are also willing to accept the challenge to help you complete the critical and difficult experimental steps in the overall plan. The extremely high professionalism and comprehensive theoretical knowledge allow us to provide you with fast and reproducible results.
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