Biotinylated Human B7-H3b CAR Detection Reagent, His,Avitag™ (CARD-LX141)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Evaluating CAR expression is an essential step in the production of CAR-T cells. Creative biolabs provides several detection reagents which are uniquely suitable for evaluation of CAR expression. Biotinylated Human B7-H3b CAR Detection Reagent, His,Avitag™ is a special detection reagent which is used to detect Human B7-H3b CAR related to the study of autoimmune diseases.

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Specifications

Target
B7-H3b

Application
FC, ELISA

Purity
>90%

Endotoxin Level
Less than 1.0 EU per μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Application Notes
The optimal working dilutions should be determined by the end user.

Diseases
autoimmune diseases

Molecular Characterization
It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1).

Conjugation
Biotinylated

Size
200ug

Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Expression
Human HEK293 cells

Host Species
Human

Species Reactivity
Human

Form
lyophilized

Images
Figure 1 Structure

Figure 2 Binding activity Evaluation

Target

Target Introduction
Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‑like and Ig C‑like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‑type and one C‑type) and shows a ubiquituous expression pattern.

Target Alternative Names
B7-H3b

UniProt ID
Q5ZPR3-1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Biotinylated Human B7-H3b CAR Detection Reagent, His,Avitag™ (CARD-LX141)

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Specifications

Target

Customer Reviews and Q&As

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