Get a real taste and understanding of the business and culture of one of the world's great research-based cellular and gene therapy discovery and development companies.
EXPOLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPOLORE MOREWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPOLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPOLORE MOREUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don’t find the answers you’re looking for, contact us for additional assistance.
EXPOLORE MORE
A germ cell tumor (GCT) is a neoplasm which arises from germ cells. GCT can be cancerous or noncancerous (benign) tumors that are mainly composed of germ cells. They are rare and account for approximately 2 to 4 % of childhood and adolescent cancer, which are diagnosed in people around 20 or younger. For malignant GCT, they can metastasize to elsewhere of the body such as the lungs, liver, lymph nodes, central nervous system and sometimes the bone, bone marrow, and other organs.
The cause of GCT is still unknown. However, several inherited defects such as the central nervous system and genitourinary tract malformations, major malformations of the lower spine can all be the possible factors to increase the risk of developing GCT.
The most common symptoms of GCT include swelling, mass that can be touched or seen, increased levels of alpha-fetoprotein (AFP), high level beta-human chorionic gonadotropin (ß-HCG), constipation, incontinence, leg weakness, abdominal pain or shortness of breath. Based on the location and size of the disease, the symptoms may vary.
People classify germ cell tumor into two groups:
Depending on the type and the growth rate of cell affected, people classify leukemia into four groups:
Overview
Ovarian germ cell tumor (OGCT) is an unusual type of ovarian cancer in which malignant (cancer) cells develop from the germ (egg) cells of the ovary. Ovarian germ cell tumors are more often in women who are 10 to 29 years old and generally affect just one ovary. Ovarian germ cell tumors are divided into the clinicopathological subtypes such as dysgerminoma (35-50% of OGCT), endodermal sinus tumor (20%), embryonal carcinoma (rare), polyembryoma (rare), choriocarcinoma (rare), teratoma and mixed GCT.
Sign and symptom
There are no obvious symptoms in the early stage. Nonetheless, tumors may be detected by regular gynecologic exams (checkups). Signs of ovarian germ cell tumor are swelling of the abdomen without weight gain in other parts of the body or bleeding from the vagina after menopause.
Associated Antigen Target
Nanoparticle Tiny Tech for Programming T Cells: A novel technology to increase the efficiency and value of your CAR-T therapy project.
LEARN MORE
End-to-end CAR Hybrid TCR (CHyT)-T Cell Therapy Development Services: A novel solution to engineer T cell to be a promising cellular therapy product with the complete TCR complex without HLA matching dependence.
LEARN MORE
TRAC-CAR-T Cell Development with CRISPR/Cas9 Technology: A novel technology to build more powerful CAR-T cells.
LEARN MORE
The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders
LEARN MORE
