Empowered by our Human Leukocyte Antigen (HLA) expertise and advanced high-resolution sequencing platforms, Creative Biolabs is fully competent and dedicated to HLA typing service to facilitate your HLA research and associated TCR research. We are committed to ultra-high-resolution HLA typing in a highly efficient way.
The Human Leukocyte Antigen (HLA) system is a series of major histocompatibility complex (MHC) proteins in humans. They are cell-surface proteins that play important roles in the immune system in humans. Studies have demonstrated that HLA is critical for disease defense, protection from cancers, organ transplant rejections. In addition, HLA can be potential biomarkers of susceptibility to some diseases or drug adverse reactions. 11 HLA types of major MHC complexes are exhibited in Fig.1. HLA is highly polymorphic, thus investigating the polymorphism is necessary and challenging.
Fig.1 HLA type of major MHC molecules.
With traditional genotyping approaches, the highly polymorphic feature makes HLA typing be challenging. Creative Biolabs has developed a dedicated NGS-based HLA typing service to meet your program requirements. We are committed to precise and high-resolution results for HLA typing service. Our HLA typing service enables fast, reliable, and most cost-effective way to fulfill your needs. Our scientists and technicians are experienced in every step with high dedication to ensuring accurate outcomes. Here is a brief workflow for your reference, including sample preparation, library construction, NGS sequencing, and data analysis, etc.
Fig.2 HLA typing workflow.
As a reliable partner in the immunology, Creative Biolabs aspires to become the best solution provider of our clients. We are committed to the HLA typing service and dedicated to reducing the overall project development timeline for our clients. Please don’t hesitate to contact us to learn more.
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