Close
Solutions
Online Inquiry

CONTACT US

USA:

UK:
Call us at:
USA:
UK:
Fax:
Email:

Guinea Pig GPLA Genotyping Service

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Equipped with state-of-the-art facilities and experienced immunology experts, Creative Biolabs is dedicated to providing high-quality GPLA genotyping services for our global clients.

Background

Guinea Pig GPLA Genotyping Service

The guinea pig MHC or guinea pig leucocyte antigen complex (GPLA) has been reported since 1973 and is classified into two classes. Class I antigens (BI, BL B3, or B4), these ubiquitous antigens correspond to mouse H2-D and H2-K antigens or to human HLA-A or HLA-B antigens. Class II and associated antigens (Ia), which have been defined as seven specificities (1, 2, 3, 4, 5, 6, 7). The GPLA antigens have a wide tissue distribution and are found on both lymphoid and nonlymphoid cells. In addition, class I and class II antigens are also present on some tumor cells including the L2C-N Leukemia. It was reported that, unlike mice or humans, most normally resting guinea pig T cells and most thymocytes have been reported to express Ia antigens. Class II antigens have also been described on several glandular epithelial cells, including guinea pig mammary gland cells.

GPLA Genotyping Services

With the advancement of genotyping approaches, GPLA genotyping has become accessible. Creative Biolabs has developed a dedicated NGS-based GPLA genotyping service to meet your program requirements. We are committed to providing more comprehensive and targeted accurate genotyping analysis results and facilitating scientific research. Our scientists and technicians are experienced in every step with high dedication to ensuring accurate outcomes.

Flow diagram of GPLA genotyping.Fig.1 Flow diagram of GPLA genotyping.

Capabilities

  • We offer pre-validated genotyping panels for GPLA.
  • We offer various fast, reliable, and most cost-effective ways in GPLA genotyping service to fulfill your needs.
  • With extensive experience and advanced platforms, we offer high-resolution results employing high standards.

Creative Biolabs' scientists are dedicated to bringing together years of valuable experience to help our clients shorten the clinical study journey. We are committed to reducing the overall project development timeline for our clients. For further details, please don't hesitate to contact us and see how we can help you reach your clinical vision.

Reference

  1. Benjamin D, Schwartz B D, Kask A M, Paul W E, et al. Structural characteristics of guinea pig major histocompatibility complex alloantigens. Leukocyte Membrane Determinants Regulating Immune Reactivity. 1976, 393-404.

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Online Inquiry

For any technical issues or products/services related questions, please leave your information below. Our team will contact you soon.

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Key Updates

Receive our latest news and insights.