Biotinylated Human uPAR CAR Detection Reagent, His,Avitag™ (CARD-LX174)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Evaluating CAR expression is an essential step in the production of CAR-T cells. Creative biolabs provides several detection reagents which are uniquely suitable for evaluation of CAR expression. Biotinylated Human uPAR CAR Detection Reagent, His,Avitag™ is a special detection reagent which is used to detect Human uPAR CAR related to the study of immune diseases.

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Specifications

Target
uPAR

Application
FC, ELISA

Purity
>90%

Endotoxin Level
Less than 1.0 EU per μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Application Notes
The optimal working dilutions should be determined by the end user.

Diseases
Autoimmune Diseases

Molecular Characterization
It contains AA Leu 23 - Arg 303 (Accession # Q03405-1)

Conjugation
Biotinylated

Size
200ug

Formulation
Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM Potassium glutamate, pH7.5. Normally trehalose is added as protectant before lyophilization.

Expression
Human HEK293 cells

Host Species
Human

Species Reactivity
Human

Images
Figure 1 Structure

Target

Target Introduction
Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.

Target Alternative Names
uPAR

UniProt ID
Q03405-1)

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Biotinylated Human uPAR CAR Detection Reagent, His,Avitag™ (CARD-LX174)

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Specifications

Target

Customer Reviews and Q&As

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