CD8A&CD8B

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Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.

Protein

CAT	Product Name	Organism	Inquiry & Datasheet
CARD-LX116	FITC-labeled Human CD8A&CD8B CAR Detection Reagent, His Tag		Add to Cart Datasheet

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CD8A&CD8B

Protein