A-431 In Vitro 7-Aminoactinomycin D Assay (Cell Viability)

CAT#: ITS-1122-YF1278
Target Cell Organism: Human
Target Cell Alternative Name: A431
Target Cell Name: A-431
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide A-431-based In Vitro 7-Aminoactinomycin D Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
A-431
Target Cell Organism
Human
Target Cell Background
A-431 is a cell line exhibiting epithelial morphology that was isolated from the epidermis of an 85-year-old female patient with epidermoid carcinoma. This cell line is one of a series of cell lines established from solid tumors by D.J. Giard, et al. and can be used in cancer, toxicology, and immuno-oncology research.
Target Cell Alternative Name
A431
Related Diseases
Epidermoid Carcinoma
Research Area
Oncology
Assay Name
In Vitro 7-Aminoactinomycin D Assay (Cell Viability)
Short Description
A-431-cell based In Vitro 7-Aminoactinomycin D Assay (Cell Viability)
Assay Description
7-Aminoactinomycin D is a fluo rescent dye that can also be used to detect viable/non-viable cells (excluded by viable cells) by fluorescence microscopy and FCM.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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