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FKBP4

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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ0991 Anti-FKBP4 (CBXF-1229) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-1229 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0992 Anti-FKBP4 (Hi52C) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat, Dog, Hamster Hi52C Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0993 Anti-FKBP4 (CBXF-0711) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-0711 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0994 Anti-FKBP4 (CBXF-2031) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-2031 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0995 Anti-FKBP4 (CBXF-0714) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-0714 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0996 Anti-FKBP4 (CBXF-1230) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-1230 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0997 Anti-FKBP4 (CBXF-0709) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat, Dog, Hamster CBXF-0709 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0998 Anti-FKBP4 (CBXF-2314) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-2314 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0999 Anti-FKBP4 (AT4D3) h(41BB-CD3ζ) CAR, pCDCAR1 Human AT4D3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1000 Anti-FKBP4 (KN382/EC1) h(41BB-CD3ζ) CAR, pCDCAR1 Cattle, Guinea pig, Hamster, Human, Mink, Mouse, Non-Human Primate, Rabbit KN382/EC1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1001 Anti-FKBP4 (CBXF-0710) h(41BB-CD3ζ) CAR, pCDCAR1 Rabbit CBXF-0710 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1002 Anti-FKBP4 (CBXF-0712) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-0712 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1003 Anti-FKBP4 (CBXF-0078) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-0078 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1004 Anti-FKBP4 (CBXF-2644) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-2644 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1005 Anti-FKBP4 (CBXF-0713) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-0713 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1006 Anti-FKBP4 (CBXF-2732) h(41BB-CD3ζ) CAR, pCDCAR1 Cattle, Guinea pig, Hamster, Human, Monkey, Rabbit CBXF-2732 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1007 Anti-FKBP4 (CBXF-3050) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-3050 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1008 Anti-FKBP4 (CBXF-3051) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-3051 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1009 Anti-FKBP4 (CBXF-3346) h(41BB-CD3ζ) CAR, pCDCAR1 Dog, Hamster, Human, Mouse, Rabbit, Rat CBXF-3346 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4415 Anti-FKBP4 (CBXF-1229) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-1229 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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