FRα

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The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP116 Anti-FRα (28BBC) h(41BB-CD3ζ) CAR, pCDCAR1 Human 28BBC Mouse scFv-4-1BB-CD3ζ Lentiviral vector NK cell   Add to Cart   Datasheet
CAR-ZP117 Anti-FRα (28BBC) h(CD28-CD3ζ) CAR, pCDCAR1 Human 28BBC Mouse scFv-CD28-CD3ζ Lentiviral vector NK cell   Add to Cart   Datasheet
CAR-ZP8849 Anti-FRα (C4) h(CD28-CD3ζ) CAR, pCDCAR1 Human C4 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8850 Anti-FRα (C4) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human C4 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-0120ZP3655 Anti-FRα (Farletuzumab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Farletuzumab Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP3656 Anti-FRα (Farletuzumab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Farletuzumab Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP3657 Anti-FRα (Mirvetuximab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Mirvetuximab Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP3658 Anti-FRα (Mirvetuximab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Mirvetuximab Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-SB-LX0259 Anti-FRα (Farletuzumab) h(CD28-CD3ζ) CAR, pSBCAR1 Human Farletuzumab Mouse scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0260 Anti-FRα (Mirvetuximab) h(CD28-CD3ζ) CAR, pSBCAR1 Human Mirvetuximab Mouse scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0322-LX41 Anti-FRα (AFRA) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human AFRA Human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0322-LX42 Anti-FRα (C4) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human C4 Human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0322-LX43 Anti-FRα (m909) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human m909 Human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0322-LX51 Anti-FRα (LK-26) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human LK-26 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0322-LX203 Anti-FRα (AFRA) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 Human AFRA Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0322-LX204 Anti-FRα (C4) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 Human C4 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0322-LX205 Anti-FRα (m909) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 Human m909 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0422-LX427 Anti-FRα (AFRA) h(CD28-41BB-CD3ζ) CAR, pMMLV Human AFRA Human scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
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