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L1CAM

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0622-ZP3195 Anti-L1CAM h(VHH1-VHH2-CD28-CD3ζ) Biepitopic CAR, pCDCAR1 Human VHH1-VHH2-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-0622-ZP3367 Anti-L1CAM h(VHH1-VHH2-4-1BB-CD3ζ) Biepitopic CAR, pCDCAR1 VHH1-VHH2-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-0722-ZP4263 Anti-L1CAM (XP7-99) h(CD28-CD3ζ) CAR, pCDCAR1 Human XP7-99 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4476 Anti-L1CAM (XP7-100) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XP7-100 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4477 Anti-L1CAM (Ab4) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Ab4 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4478 Anti-L1CAM (XP7-101) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XP7-101 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4479 Anti-L1CAM (XP7-102) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XP7-102 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4480 Anti-L1CAM (cA10-A3) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human cA10-A3 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4481 Anti-L1CAM (G6) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human G6 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4482 Anti-L1CAM (HzA10A3-2.1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human HzA10A3-2.1 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX243 Anti-L1CAM (X11X243) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X11X243 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX244 Anti-L1CAM (X11X244) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X11X244 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX634 Anti-L1CAM (X11X236) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X236 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX635 Anti-L1CAM (X11X237) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X237 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX636 Anti-L1CAM (X11X238) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X238 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX637 Anti-L1CAM (X11X239) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X239 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX638 Anti-L1CAM (X11X240) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X240 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX639 Anti-L1CAM (X11X241) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X241 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX640 Anti-L1CAM (X11X242) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X242 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-LX641 Anti-L1CAM (X11X243) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X11X243 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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