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PCBP1

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This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY1579 Anti-PCBP1 (CBFYH-2698) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2698 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1580 Anti-PCBP1 (CBFYH-2699) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2699 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1581 Anti-PCBP1 (CBFYH-2700) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2700 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4832 Anti-PCBP1 (CBFYH-2698) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-2698 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4833 Anti-PCBP1 (CBFYH-2699) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-2699 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4834 Anti-PCBP1 (CBFYH-2700) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-2700 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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