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TDG

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

TDG belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a key role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YJ233 Anti-TDG (1142) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1142 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ234 Anti-TDG (1511) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1511 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ235 Anti-TDG (3C11) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3C11 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ236 Anti-TDG (AT2F7) h(41BB-CD3ζ) CAR, pCDCAR1 Human AT2F7 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ733 Anti-TDG (1142) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1142 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ734 Anti-TDG (1511) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1511 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ735 Anti-TDG (3C11) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3C11 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ736 Anti-TDG (AT2F7) h(CD28-CD3ζ) CAR, pCDCAR1 Human AT2F7 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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