Creative Biolabs-Immuno-oncology

Anti-HMGB1 (clone 31G6Z1G) SynExpress C-mCh-I10-Sa Synthetic CD4+ T cells (CAT#: ITS-1224-CR187)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target HMGB1 (clone 31G6Z1G). We employs the pGEX (CMV-mCherry-IL-10-SaII) vector components and the SynExpress system of the Multiple base pair Insertion/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
HMGB1
Clone
31G6Z1G
Species Reactivity
Human; Mouse
Cell Source
Synthetic CD4+ T cells
Sensor Gene
mCherry
Promoter
CMV
Effector Gene
IL-10
Insertion Sites
SaII
Gene Modification
Insertion
Modification Domain
Multiple base pair
Carrier Type
pGEX
Transformation Accuracy
0.86
Cell Culture
Adherent Culture
Case Studies
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