Anti-CEACAM5 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2847-FY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CEACAM5 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
CEACAM5

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
1048

UniProt ID
P06731

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0451-CQ	161 (NCRC16)	Mouse	Human	IgG1	Colon cancer cell lines
DMAb-0454-CQ	Arcitumomab	Rabbit		IgG	Carcinoembryonic antigen (CEA)
DMAb-0455-CQ	By114	Mouse	Human	IgG1, κ	B cell Lymphoma cells
DMAb-0456-CQ	C365D3(NCRC23)	Mouse	Human	IgG1	Made to Human CD66e
DMAb-0457-CQ	C66/1009	Mouse	Human	IgG2a, κ	Recombinant Full length human CEA protein
DMAb-0458-CQ	C66/1030	Mouse	Human	IgG1, κ	Recombinant Full length human CEA protein
DMAb-0459-CQ	C66/1260	Mouse	Human	IgG2a, κ	Purified human CEA protein
DMAb-0460-CQ	C66/1291	Mouse	Human	IgG1	Recombinant Full length human CEA protein
DMAb-0461-CQ	C66/1292	Mouse	Human	IgG2b	Recombinant Full length human CEA protein
DMAb-0462-CQ	C66/195	Mouse		IgG1, κ	Recombinant Full length human CEA protein
DMAb-0463-CQ	C66/261	Mouse		IgG1, κ	Recombinant Full length human CEA protein
DMAb-0465-CQ	CEA31	Mouse		IgG1, κ	Human colon carcinoma extract
DMAb-0466-CQ	COL-1	Mouse	Human	IgG2a, κ	Colon carcinoma cell extract for the CEACAM1 antibody
DMAb-0467-CQ	PARLAM4	Mouse	Human	IgG1	Human CEA
DMAb-0468-CQ	SPM330	Mouse		IgG1, κ	Purified human CEA protein
DMAb-0469-CQ	SPM506	Mouse		IgG1, κ	Human colon carcinoma extract
DMAb-0470-CQ	SPM541	Mouse		IgG1, κ	Human colon carcinoma extract
DMAb-0471-CQ	SPM551	Mouse		IgG1, κ	Human recombinant CEA protein
DMAb-0472-CQ	SPM584	Mouse	Human	IgG2a, κ	Human colon carcinoma extract
DMAb-0474-CQ	CCM661	Mouse	Human	IgG2a, κ	Human Full length recombinant protein
DMAb-0475-CQ	CCAM5-1	Mouse	Human	IgG2b, κ	Human Full length recombinant protein
DMAb-0476-CQ	C19	Mouse	Human	IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-CEACAM5 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2847-FY)

Specifications

Target

Customer Reviews and Q&As

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