Anti-CFL1 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0468-WJ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CFL1 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
CFL1

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
1072

UniProt ID
P23528

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0469-WJ	AF2C2	Mouse		IgG2a, κ	Recombinant protein corresponding to human cofilin, expressed in E. coli
DMAb-0470-WJ	AT1C1	Mouse		IgG1, κ	Cofilin 1 antibody was raised in mouse using recombinant human Cofilin 1 (1-166aa) purified from E. coli as the immunogen
DMAb-0472-WJ	GT567	Mouse		IgG2a	Recombinant fragment contains a sequence corresponding to a region within aa1 and 166 of Cofilin 1
DMAb-0469-WJ	AF2C2	Mouse		IgG2a, κ	Recombinant full length Cofilin protein (Human)
DMAb-3456CQ	BA0431	Mouse		IgG2a, κ	Amino acids 1-167 of Human Cofilin
DMAb-3457CQ	BA0313	Rabbit		IgG	Synthetic peptide from Human Cofilin aa 1-100
DMAb-3458CQ	BA0064	Rabbit		IgG	Synthetic peptide from residues in Human Cofilin

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-CFL1 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0468-WJ)

Specifications

Target

Customer Reviews and Q&As

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