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Anti-MYD88 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2531-FY)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-MYD88 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

  • Target
  • MYD88
  • Vector Name
  • pVAX1
  • Vector Description
  • pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.
  • Vector Promoter
  • CMV
  • Vector Tag or Fusion
  • Untagged
  • Delivery Method
  • Transfection
  • Cloning Method
  • Restriction Enzyme ⁄ MCS
  • Constitutive or Inducible System
  • Constitutive
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.
  • Background
  • DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

  • Entrez Gene ID
  • 4615
Sub CAT. DMAb Clone DMAb Host Target Species DMAb Isotype DMAb Immunogen  
DMAb-2531-FY 2E9C2 Mouse Human IgG2b Recombinant protein corresponding to amino acids 176 to 280 of human MyD88
DMAb-2532-FY CBFYM-0092 Mouse Human IgG2b, k Recombinant human MYD88 (1-309aa) purified from E. coli
DMAb-2533-FY CBFYM-0124 Rat Human IgG2a E. coli-derived recombinant human MyD88, Met1-Pro296
DMAb-2534-FY CBFYM-0164 Mouse Human IgG1, k Synthetic peptide (68 DFEYLEIRQLETQADPTGR 86) of MyD88 protein
DMAb-2535-FY CBFYM-2899 Mouse Human IgG2b Recombinant protein corresponding to aa176-280 from human MyD88
DMAb-2536-FY CBFYM-2900 Mouse Human IgG2a MYD88 antibody was raised in mouse using a full length recombinant protein of human MYD88 (NP_002459) produced in HEK293T cells,
DMAb-2537-FY CBFYM-2901 Mouse Human Recombinant protein corresponding to aa1-309 from human MYD88 expressed in E. coli
DMAb-2538-FY CBFYM-2902 Mouse Human IgG2b
DMAb-2539-FY CBFYM-2903 Mouse Human IgG1
DMAb-2540-FY CBFYM-2904 Rabbit Human IgG Synthetic peptide corresponding to residues surrounding Cys233 of human MyD88 protein
DMAb-2541-FY CBFYM-2905 Mouse Rat

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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