Anti-TMPO DNA-encoded mAb (DMAb), pVAX1 (DMAb-0277-YJ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-TMPO DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
TMPO

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
7112

UniProt ID
P42166

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0277-YJ	8S37	Mouse	Human	IgG1	Human recombinant Thymopoietin
DMAb-0163-YJ	RL29	Armenian Hamster	Rat	IgG
DMAb-0086-YJ	3A3	Mouse	Human	IgG1, κ	Synthetic peptide conjugated to KLH derived from within residues 650-750 of Human LAP2 alpha.
DMAb-0160-YJ	6E10	Mouse		IgG1	Synthetic peptide: GEQRKDVYVQLYLQHLTARNRP, corresponding to amino acids 29-50 of Human LAP2, common to all isoforms.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-TMPO DNA-encoded mAb (DMAb), pVAX1 (DMAb-0277-YJ)

Specifications

Target

Customer Reviews and Q&As

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