The vector of anti-FRα (Folate receptor-alpha) chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human FRα (Folate receptor-alpha) . The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-FRα (Folate receptor-alpha) antibody linked to CD3ζ signaling domains. And the vector product was designed for the treatment of FRα positive human cancers.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-LC165||Anti-FRA (C4) h(CD3ζ) CAR, pCDCAR1|
|CAR-MZ155||Anti-FRα (MOv19) h(CD137-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC532||Lenti-FRA CAR (scFv-ICOS-CD3ζ, MOv19) Viral Particle|
|CAR-LC040||Anti-FRA (MOv19) h(ICOS-CD3ζ) CAR, pCDCAR1|
|CAR-LC164||Anti-FRA (C4) h(CD28-CD3ζ) CAR, pCDCAR1|
|CAR-LC006||Anti-FRA (C4) h(CD27-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC648||Lenti-FRA CAR (scFv-CD28-CD3ζ, C4) Viral Particle|
|VP-CAR-LC849||Lenti-FRα (Folate receptor-alpha) CAR (scFv-CD3ζ, MOv19) Viral Particle|
|VP-CAR-LC512||Lenti-FRA CAR (scFv-CD27-CD3ζ , C4) Viral Particle|
|VP-CAR-LC850||Lenti-FRα (Folate receptor-alpha) CAR (scFv-CD137-CD3ζ, MOv19) Viral Particle|
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