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Anti-CD1d–α-GalCer T cell receptor (9B4), pCDTCR1 (TCR-C033Z)

The vector of anti-CD1d–α-GalCer T cell receptor (TCR) is constructed for the engineering of T cell to target CD1d–α-GalCer. The T cells are genetically modified through transduction with a lentiviral vector expressing CD1d–α-GalCer-specific T cell receptor. And the vector product was designed for the treatment of Cancer and autoimmune diseases.

Details

  • Target
  • CD1d-α-GalCer
  • Format
  • Non-modified
  • Targeting Diseases
  • Cancer and autoimmune diseases
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Clone
  • 9B4
  • Antibody Host
  • Human

Target

  • Gene Name
  • Alpha-Galactosylceramide
  • Official Symbol
  • CD1d–α-GalCer
  • Synonyms
  • α-GalCer; Alpha-Galactosylceramide
  • Introduction
  • The natural antigens of group 2 CD1 are not well-characterized, but a synthetic glycolipid, alpha-galactosylceramide, originally isolated from a compound found in a marine sponge, has strong biologic activity.
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