Lenti-CD23 CAR (scFv-CD4ζ, Tü1)-VP(VP-CAR-LC239)

The ready-to-use lentiviral particles of Lenti-CD23 CAR (scFv-CD4ζ, Tü1)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (Tü1)-CD4-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.


Specifications


Type of Therapeutics
Chimeric Antigen Receptor
Target
CD23
Expression Cassette
scFv (Tü1)-CD4-CD3ζ
Clone
Tü1
Promotor
CMV
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Chronic lymphocytic leukemia (CLL)

Target


Introduction
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Alternative Names
FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23; FCE2; CD23A; IGEBF; CLEC4J; BLAST-2; Chronic lymphocytic leukemia; leukemia; CLL; scFv; FcεRIγ; Chimeric antigen receptor; T cell; Retrovirus; CARs; Lentivirus; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; Tü1
Gene ID

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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Tel: 44-207-048-3343

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