The vector of anti-CD33 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD33. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD33 antibody linked to CD4 transmembrane domain and FcεRIγ signaling domains. And the vector product was designed for the treatment of acute myeloid leukemia (AML).
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-ZP152||Anti-CD33 (hM195) h(CD28-CD3ζ) CAR, pCDCAR1|
|CAR-YF219||Anti-CD33 (My9-6) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC675||Lenti-CD33 CAR (scFv-41BB-CD3ζ, My9-6) Viral Particle|
|CAR-YF084||Anti-CD33 (CBL-YF026) h(4-1BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC639||Lenti-CD33 CAR (scFv-CD28-CD3ζ) Viral Particle|
|VP-CAR-LC104||Lenti-CD33 CAR (scFv-CD8-CD3ζ, CAMPATH-1H) Viral Particle|
|CAR-LC197||Anti-CD33 (My9-6) h(41BB-CD3ζ) CAR, pCDCAR1|
|CAR-YF166||Anti-CD33 (CBL-YF053) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC853||Lenti-CD33 CAR (scFv-CD28-CD3ζ, DRB2) Viral Particle|
|VP-CAR-LC673||Lenti-CD33 CAR (scFv-41BB-CD3ζ, DRB2) Viral Particle|
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