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CD33

Myeloid cell surface antigen CD33, is a transmembrane receptor expressed on cells of myeloid lineage. It has numerous synonymous names including Siglec-3, sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67 or p67. CD33 is broadly expressed on acute myeloid leukemia (AML) blasts and, possibly some leukemic stem cells and has therefore been exploited as target for therapeutic antibodies. Some antibody-drug conjugates such as gemtuzumab ozogamicin target at CD33 for the treatment of patients with acute myeloid leukemia.

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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-M311-2 Anti-CD33 scFv h(CD28) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M311-G Anti-CD33 scFv h(FcεRIγ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M311-Z Anti-CD33 scFv h(CD3ζ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M311-2G Anti-CD33 scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M311-2Z Anti-CD33 scFv h(CD28-CD3ζ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M311-4G Anti-CD33 scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M311-4Z Anti-CD33 scFv h(CD4-CD3ζ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M311-8Z Anti-CD33 scFv h(CD8-CD3ζ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M311-BZ Anti-CD33 scFv h(41BB-CD3ζ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M311-CZ Anti-CD33 scFv h(b2c-CD3ζ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M311-2BZ Anti-CD33 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M311-2XZ Anti-CD33 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human CMA-676 Humanized Rat scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC155 Anti-CD33 h(CD28-CD3ζ) CAR, pCDCAR1 Human Mouse scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC194 Anti-CD33 (M195) h(41BB-CD3ζ) CAR, pCDCAR1 Human M195 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC195 Anti-CD33 (DRB2) h(41BB-CD3ζ) CAR, pCDCAR1 Human DRB2 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC196 Anti-CD33 (m2H12) h(41BB-CD3ζ) CAR, pCDCAR1 Human m2H12 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC197 Anti-CD33 (My9-6) h(41BB-CD3ζ) CAR, pCDCAR1 Human My9-6 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC280 Anti-CD33 (Gemtuzumab) h(CD3ζ, TetR/Tip) Conditional CAR, pCDCAR1 Human Gemtuzumab Human scFv-TetR/Tip-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ004 Anti-CD33 scFv h(DAP10) CAR, pCDCAR1 Human Human scFv-DAP10 Retroviral T cell   Add to Cart   Datasheet
CAR-MZ158 Anti-CD33 (DRB2) h(CD28-CD3ζ) CAR, pCDCAR1 Human DRB2 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-YF217 Anti-CD33 (M195) h(CD28-CD3ζ) CAR, pCDCAR1 Human M195 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF218 Anti-CD33 (M2H12) h(CD28-CD3ζ) CAR, pCDCAR1 Human M2H12 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF219 Anti-CD33 (My9-6) h(CD28-CD3ζ) CAR, pCDCAR1 Human My9-6 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP023 Anti-CD33 h(CD28-CD3ζ) CAR, pCDCAR1 Human Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP152 Anti-CD33 (hM195) h(CD28-CD3ζ) CAR, pCDCAR1 Human hM195 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP153 Anti-CD33 (hM195) h(41BB-CD3ζ) CAR, pCDCAR1 Human hM195 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP762 Anti-CD33 (9C3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 9C3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP763 Anti-CD33 (9C3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9C3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP764 Anti-CD33 (2D12-G4) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2D12-G4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP765 Anti-CD33 (2D12-G4) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2D12-G4 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP766 Anti-CD33 (3E1-D1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3E1-D1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP767 Anti-CD33 (3E1-D1) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3E1-D1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP768 Anti-CD33 (MY9) h(CD28-CD3ζ) CAR, pCDCAR1 Human MY9 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP769 Anti-CD33 (MY9) h(41BB-CD3ζ) CAR, pCDCAR1 Human MY9 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP770 Anti-CD33 (PWS44) h(CD28-CD3ζ) CAR, pCDCAR1 Human PWS44 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP826 Anti-CD33 (1G10) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1G10 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP827 Anti-CD33 (1G10) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1G10 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP828 Anti-CD33 (1E4) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1E4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP829 Anti-CD33 (1E4) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1E4 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP830 Anti-CD33 (1E10) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1E10 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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