CD33

Myeloid cell surface antigen CD33, is a transmembrane receptor expressed on cells of myeloid lineage. It has numerous synonymous names including Siglec-3, sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67 or p67. CD33 is broadly expressed on acute myeloid leukemia (AML) blasts and, possibly some leukemic stem cells and has therefore been exploited as target for therapeutic antibodies. Some antibody-drug conjugates such as gemtuzumab ozogamicin target at CD33 for the treatment of patients with acute myeloid leukemia.


CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC155 T cell Second ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-LC194 T cell Second M195 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC195 T cell Second DRB2 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC196 T cell Second m2H12 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC197 T cell Second My9-6 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC280 T cell First Gemtuzumab ~8kb Lentiviral scFv-TetR/Tip-CD3ζ Human Inquiry
CAR-MZ004 T cell First ~8kb Retroviral scFv-DAP10 Human Inquiry
CAR-MZ158 T cell Second DRB2 ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-1-M311-2 T cell First CAMPATH-1H 8kb Lentiviral scFv-CD28 Humanized Rat Inquiry
CAR-T-1-M311-G T cell First CAMPATH-1H 8kb Lentiviral scFv-FcεRIγ Humanized Rat Inquiry
CAR-T-1-M311-Z T cell First CAMPATH-1H 8kb Lentiviral scFv-CD3ζ Humanized Rat Inquiry
CAR-T-2-M311-2G T cell Second CAMPATH-1H 8kb Lentiviral scFv-CD28-FcεRIγ Humanized Rat Inquiry
CAR-T-2-M311-2Z T cell Second CAMPATH-1H 8kb Lentiviral scFv-CD28-CD3ζ Humanized Rat Inquiry
CAR-T-2-M311-4G T cell Second CAMPATH-1H 8kb Lentiviral scFv-CD4-FcεRIγ Humanized Rat Inquiry
CAR-T-2-M311-4Z T cell Second CAMPATH-1H 8kb Lentiviral scFv-CD4-CD3ζ Humanized Rat Inquiry
CAR-T-2-M311-8Z T cell Second CAMPATH-1H 8kb Lentiviral scFv-CD8-CD3ζ Humanized Rat Inquiry
CAR-T-2-M311-BZ T cell Second CAMPATH-1H 8kb Lentiviral scFv-41BB-CD3ζ Humanized Rat Inquiry
CAR-T-2-M311-CZ T cell Second CAMPATH-1H 8kb Lentiviral scFv-b2c-CD3ζ Humanized Rat Inquiry
CAR-T-3-M311-2BZ T cell Third CAMPATH-1H 8kb Lentiviral scFv-CD28-41BB-CD3ζ Humanized Rat Inquiry
CAR-T-3-M311-2XZ T cell Third CAMPATH-1H 8kb Lentiviral scFv-CD28-OX40-CD3ζ Humanized Rat Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC100 CAMPATH-1H Lentivirus Second scFv (CAMPATH-1H)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC101 CAMPATH-1H Lentivirus Second scFv (CAMPATH-1H)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC102 CAMPATH-1H Lentivirus Second scFv (CAMPATH-1H)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC103 CAMPATH-1H Lentivirus Second scFv (CAMPATH-1H)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC104 CAMPATH-1H Lentivirus Second scFv (CAMPATH-1H)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC105 CAMPATH-1H Lentivirus Second scFv (CAMPATH-1H)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC106 CAMPATH-1H Lentivirus Second scFv (CAMPATH-1H)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC107 CAMPATH-1H Lentivirus Third scFv (CAMPATH-1H)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC108 CAMPATH-1H Lentivirus Third scFv (CAMPATH-1H)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC639 Lentivirus Second scFv-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC672 M195 Lentivirus Second scFv (M195)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC673 DRB2 Lentivirus Second scFv (DRB2)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC674 m2H12 Lentivirus Second scFv (m2H12)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC675 My9-6 Lentivirus Second scFv (My9-6)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC853 DRB2 Lentivirus Second scFv (DRB2)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC97 CAMPATH-1H Lentivirus First scFv (CAMPATH-1H)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC98 CAMPATH-1H Lentivirus Second scFv (CAMPATH-1H)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC99 CAMPATH-1H Lentivirus First scFv (CAMPATH-1H)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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Tel: 44-207-048-3343

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