The vector of anti-gp100 chimeric antigen receptor(CAR) is constructed for the engineering of T cell to target human gp100. The T cell is genetically modified through transduction with a lentiviral vector expressing anti-gp100 VHH linked to CD3-zeta signaling domains. And the vector product was designed for the treatment of melanoma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-T-2-M552-CZ||Anti-gp100 VHH h(b2c-CD3ζ) CAR, [T]|
|CAR-T-1-M552-G||Anti-gp100 VHH h(FcεRIγ) CAR, [T]|
|CAR-T-2-M552-BZ||Anti-gp100 VHH h(41BB-CD3ζ) CAR, [T]|
|CAR-T-2-M552-4Z||Anti-gp100 VHH h(CD4-CD3ζ) CAR, [T]|
|CAR-T-3-M552-2XZ||Anti-gp100 VHH h(CD28-OX40-CD3ζ) CAR, [T]|
|CAR-T-2-M552-8Z||Anti-gp100 VHH h(CD8-CD3ζ) CAR, [T]|
|CAR-T-2-M552-4G||Anti-gp100 VHH h(CD4-FcεRIγ) CAR, [T]|
|CAR-T-2-M552-2G||Anti-gp100 VHH h(CD28-FcεRIγ) CAR, [T]|
|CAR-T-3-M552-2BZ||Anti-gp100 VHH h(CD28-41BB-CD3ζ) CAR, [T]|
|CAR-T-1-M552-2||Anti-gp100 VHH h(CD28) CAR, [T]|
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