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gp100

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type 		Generation Antibody
Clone 		Vector
Length 		Vector
Type 		Vector Design Antibody
Host 		Data
sheet		 Price
CAR-T-1-M552-2 T cell First GPA7 8kb Lentiviral VHH-CD28 Camelid Inquiry
CAR-T-1-M552-G T cell First GPA7 8kb Lentiviral VHH-FcεRIγ Camelid Inquiry
CAR-T-1-M552-Z T cell First GPA7 8kb Lentiviral VHH-CD3ζ Camelid Inquiry
CAR-T-2-M552-2G T cell Second GPA7 8kb Lentiviral VHH-CD28-FcεRIγ Camelid Inquiry
CAR-T-2-M552-2Z T cell Second GPA7 8kb Lentiviral VHH-CD28-CD3ζ Camelid Inquiry
CAR-T-2-M552-4G T cell Second GPA7 8kb Lentiviral VHH-CD4-FcεRIγ Camelid Inquiry
CAR-T-2-M552-4Z T cell Second GPA7 8kb Lentiviral VHH-CD4-CD3ζ Camelid Inquiry
CAR-T-2-M552-8Z T cell Second GPA7 8kb Lentiviral VHH-CD8-CD3ζ Camelid Inquiry
CAR-T-2-M552-BZ T cell Second GPA7 8kb Lentiviral VHH-41BB-CD3ζ Camelid Inquiry
CAR-T-2-M552-CZ T cell Second GPA7 8kb Lentiviral VHH-b2c-CD3ζ Camelid Inquiry
CAR-T-3-M552-2BZ T cell Third GPA7 8kb Lentiviral VHH-CD28-41BB-CD3ζ Camelid Inquiry
CAR-T-3-M552-2XZ T cell Third GPA7 8kb Lentiviral VHH-CD28-OX40-CD3ζ Camelid Inquiry

TCR Vector Products Product list:

Catalog Target Target
Species 		Antibody
Clone 		scFv-Host
Animal 		Vector
length 		Vector
Type 		Epitope Format HLA Data
sheet		 Price
TCR-C075Z gp100 Human G7 Human ~8kb Lentiviral WTWNRQLYPEWTEAQRLD Non-modified HLA-DR4 Inquiry
TCR-C076Z gp100 Human gp100 Human ~8kb Lentiviral YLEPGPVTA Non-modified HLA-A2 Inquiry
TCR-C077Z gp100 Human PMEL17 Human ~8kb Lentiviral YLEPGPVTA Non-modified HLA-A2 Inquiry
TCR-C078Z gp100 Human R6C12 Human ~8kb Lentiviral aa 209-217 Non-modified HLA-A*0201 Inquiry
TCR-C079Z gp100 Human R6C12 Murinized ~8kb Lentiviral aa 209-217 Murinized and Codon-optimized and Cysteine-modi?ed HLA-A*0201 Inquiry
TCR-C080Z gp100 Human gp100(154) Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-C081Z gp100 Human MPD Human ~8kb Lentiviral YLEPGPVTA Non-modified HLA-A*0201 Inquiry
TCR-C082Z gp100 Human 296 Human ~8kb Lentiviral YLEPGPVTA Non-modified HLA-A2 Inquiry
TCR-C083Z gp100 Human L2G2 Human ~8kb Lentiviral aa 209-217 Non-modified HLA-A*0201 Inquiry
TCR-L023 gp100 Human Mouse 6700-8070bp retroviral vector KTWGQYWQV Non-modified TCR HLA-A2 Inquiry
TCR-L023Z gp100 Human Mouse 8kb Lentiviral KTWGQYWQV Non-modified HLA-A2 Inquiry
TCR-L024 gp100 Human Human 6700-8070bp retroviral vector IMDQVPFSV Non-modified TCR HLA-A2 Inquiry
TCR-L024Z gp100 Human Human 8kb Lentiviral IMDQVPFSV Non-modified HLA-A2 Inquiry
TCR-L025 gp100 Human Murinized (from Human) 6700-8070bp retroviral vector IMDQVPFSV Murinized TCR HLA-A2 Inquiry
TCR-L025Z gp100 Human Murinized (from Human) 8kb Lentiviral IMDQVPFSV Murinized HLA-A2 Inquiry
TCR-L026 gp100 Human Murinized (from Human) 6700-8070bp retroviral vector IMDQVPFSV Murinized and Cysteine-modified TCR HLA-A2 Inquiry
TCR-L026Z gp100 Human Murinized (from Human) 8kb Lentiviral IMDQVPFSV Murinized and Cysteine-modified HLA-A2 Inquiry
TCR-L027 gp100 Human Human 6700-8070bp retroviral vector YLEPGPVTA Non-modified TCR HLA-A2 Inquiry
TCR-L027Z gp100 Human Human 8kb Lentiviral YLEPGPVTA Non-modified HLA-A2 Inquiry
TCR-L028 gp100 Human Mouse 6700-8070bp retroviral vector gp100[154-162] Non-modified TCR HLA-A2 Inquiry
TCR-L029 gp100 Human Human 3111bp retroviral vector YLEPGPVTA Affinity enhanced HLA-A2 Inquiry
TCR-L029Z gp100 Human Human 8kb Lentiviral YLEPGPVTA Affinity enhanced HLA-A2 Inquiry
TCR-L030 gp100 Human Human 3111bp retroviral vector YLEPGPVTA Cysteine-modified TCR HLA-A2 Inquiry
TCR-L030Z gp100 Human Human 8kb Lentiviral YLEPGPVTA Cysteine-modified HLA-A2 Inquiry
TCR-L031 gp100 Human Murinized (from Human) 6700-8070bp retroviral vector KTWGQYWQV Murinized TCR HLA-A*0201 Inquiry
TCR-L031Z gp100 Human Murinized (from Human) 8kb Lentiviral KTWGQYWQV Murinized HLA-A*0201 Inquiry
TCR-L261 gp100 Human gp100 Mouse ~8kb Lentiviral IMDQVPFSV Non-modified HLA-A2 Inquiry
TCR-L365 gp100 Human T2(1)C Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L366 gp100 Human Sp(0.01)A Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L367 gp100 Human T2(1)A Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L368 gp100 Human T2(1)B Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L369 gp100 Human T2(1)K Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L370 gp100 Human Sp(0.1)A10 Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L371 gp100 Human T2(1)J Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L372 gp100 Human T2(1)N Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L373 gp100 Human T2(1)H Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L374 gp100 Human T2(1)P Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L375 gp100 Human Sp(0.01)B Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L376 gp100 Human Sp(0.01)C Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L377 gp100 Human Sp(1) A Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L378 gp100 Human T2(1)G Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L379 gp100 Human T2(1)M Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L380 gp100 Human T2(1)O Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L381 gp100 Human T2(1)Q Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L382 gp100 Human T2(1)T Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L383 gp100 Human T2(1)Cpost Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L384 gp100 Human T2(0.01)A Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L385 gp100 Human Sp(0.01)K Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L386 gp100 Human Sp(0.01)D Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L387 gp100 Human T2(1)S Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L388 gp100 Human Sp(5)B Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L389 gp100 Human T2(1) U Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L390 gp100 Human T2(1) I Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L391 gp100 Human T2(1) L Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L392 gp100 Human T2(1) R Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry
TCR-L393 gp100 Human Sp(1)B Mouse ~8kb Lentiviral KTWGQYWQV Non-modified HLA-A*0201 Inquiry

TCR Viral Particles Product list:

Catalog Target
Species 		Antibody
Clone 		scFv-Host
Animal 		Packaging
System 		Epitope Format Titer Data
sheet		 Price
VP-TCR-C379 Human G7 Human Lentivirus WTWNRQLYPEWTEAQRLD Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C380 Human gp100 Human Lentivirus YLEPGPVTA Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C381 Human PMEL17 Human Lentivirus YLEPGPVTA Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C382 Human R6C12 Human Lentivirus aa 209-217 Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C383 Human gp100(154) Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C384 Human MPD Human Lentivirus YLEPGPVTA Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C385 Human 296 Human Lentivirus YLEPGPVTA Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C386 Human L2G2 Human Lentivirus aa 209-217 Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C388 Human T2(1)C Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C389 Human Sp(0.01)A Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C390 Human T2(1)A Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C391 Human T2(1)B Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C392 Human T2(1)K Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C393 Human Sp(0.1)A10 Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C394 Human T2(1)J Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C395 Human T2(1)N Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C396 Human T2(1)H Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C397 Human T2(1)P Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C398 Human Sp(0.01)B Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C399 Human Sp(0.01)C Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C400 Human Sp(1) A Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C401 Human T2(1)G Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C402 Human T2(1)M Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C403 Human T2(1)O Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C404 Human T2(1)Q Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C405 Human T2(1)T Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C406 Human T2(1)Cpost Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C407 Human T2(0.01)A Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C408 Human Sp(0.01)K Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C409 Human Sp(0.01)D Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C410 Human T2(1)S Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C411 Human Sp(5)B Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C412 Human T2(1) U Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C413 Human T2(1) I Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C414 Human T2(1) L Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C415 Human T2(1) R Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C416 Human Sp(1)B Mouse Lentivirus KTWGQYWQV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C417 Human Human Lentivirus IMDQVPFSV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C418 Human Murinized (from Human) Lentivirus IMDQVPFSV Murinized TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C419 Human Murinized (from Human) Lentivirus IMDQVPFSV Murinized and Cysteine-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C420 Human Human Lentivirus YLEPGPVTA Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C421 Human Human Lentivirus YLEPGPVTA Cysteine-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C422 Human Murinized (from Human) Lentivirus KTWGQYWQV Murinized TCR > 10⁷ IFU/ml Inquiry
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