The vector of anti-GPC3 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human GPC3. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-GPC3 antibody linked to a CD8 hinge-transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for the treatment of hepatocellular carcinoma (HCC).
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|TCR-ZP052||Mouse anti-GPC3 T cell receptor (2), pCDTCR1|
|TCR-C089Z||Murinized anti-GPC3 T cell receptor (P2-1), pCDTCR1|
|CAR-YF067||Anti-GPC3 (CBL-YF017) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC267||Lenti-GPC3 CAR (scFv-CD28-41BB-CD3ζ, 9C2) Viral Particle|
|CAR-LC049||Anti-GPC3 (GC33) h(CD28-41BB-CD3ζ) CAR, pCDCAR1|
|CAR-LC090||Anti-GPC3 h(CD3ζ) CAR, pCDCAR1|
|CAR-LC048||Anti-GPC3 (GC33) h(41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC262||Lenti-GPC3 CAR (scFv-CD4-FcεRIγ, 9C2) Viral Particle|
|VP-CAR-LC264||Lenti-GPC3 CAR (scFv-CD8-CD3ζ, 9C2) Viral Particle|
|VP-CAR-LC581||Lenti-GPC3 CAR (scFv-CD28-41BB-CD3ζ) Viral Particle|
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