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Glypican-3 (GPC3)

Glypican 3 (GPC3), also known as DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1, is encoded by the GPC3 gene that belongs to the member of the glypican family. This protein is highly expressed in embryonal tissues such as the developing intestine and the mesoderm-derived tissue, and its expression is downregulated in most adult tissue. GPC3 is able not only to bind more than one growth factor, but also to functionally affect the signaling of different growth factors. GPC3 is related to hepatocellular carcinoma, Wilm's tumor, colorectal malignancie, neuroblastoma, medullary cell carcinoma, mesothelioma, ovarian cancer and breast cancer.

Associated Disease
  • CAR Vector Products
  • TCR Vector Products
  • CAR Viral Particles
  • TCR Viral Particles
CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type  
CAR-T-1-L342-2 Anti-GPC3 scFv h(CD28) CART, pCDCAR1 Human 9C2 Mouse scFv-CD28 Lentiviral T cell   Inquiry
  Datasheet
CAR-T-1-L342-G Anti-GPC3 scFv h(FcεRIγ) CART, pCDCAR1 Human 9C2 Mouse scFv-FcεRIγ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-1-L342-Z Anti-GPC3 scFv h(CD3ζ) CART, pCDCAR1 Human 9C2 Mouse scFv-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-L342-2G Anti-GPC3 scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human 9C2 Mouse scFv-CD28-FcεRIγ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-L342-2Z Anti-GPC3 scFv h(CD28-CD3ζ) CART, pCDCAR1 Human 9C2 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-L342-4G Anti-GPC3 scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human 9C2 Mouse scFv-CD4-FcεRIγ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-L342-4Z Anti-GPC3 scFv h(CD4-CD3ζ) CART, pCDCAR1 Human 9C2 Mouse scFv-CD4-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-L342-8Z Anti-GPC3 scFv h(CD8-CD3ζ) CART, pCDCAR1 Human 9C2 Mouse scFv-CD8-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-L342-BZ Anti-GPC3 scFv h(41BB-CD3ζ) CART, pCDCAR1 Human 9C2 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-2-L342-CZ Anti-GPC3 scFv h(b2c-CD3ζ) CART, pCDCAR1 Human 9C2 Mouse scFv-b2c-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-3-L342-2BZ Anti-GPC3 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human 9C2 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-T-3-L342-2XZ Anti-GPC3 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human 9C2 Mouse scFv-CD28-OX40-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC090 Anti-GPC3 h(CD3ζ) CAR, pCDCAR1 Human Human scFv-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC091 Anti-GPC3 h(CD28-CD3ζ) CAR, pCDCAR1 Human Human scFv-CD28-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC046 Anti-GPC3 (GC33) h(CD3ζ) CAR, pCDCAR1 Human GC33 Mouse scFv-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-LC047 Anti-GPC3 (GC33) h(CD28-CD3ζ) CAR, pCDCAR1 Human GC33 Mouse scFv-CD28-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-LC092 Anti-GPC3 h(41BB-CD3ζ) CAR, pCDCAR1 Human Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC093 Anti-GPC3 h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human Human scFv-CD28-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC048 Anti-GPC3 (GC33) h(41BB-CD3ζ) CAR, pCDCAR1 Human GC33 Mouse scFv-41BB-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-LC049 Anti-GPC3 (GC33) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human GC33 Mouse scFv-CD28-41BB-CD3ζ Retroviral T cell   Inquiry
  Datasheet
CAR-LC178 Anti-GPC3 (3E11) h(CD3ζ) CAR, pCDCAR1 Human 3E11 Human scFv-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC179 Anti-GPC3 (3E11) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3E11 Human scFv-CD28-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC180 Anti-GPC3 (3E11) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human 3E11 Human scFv-CD28-41BB-CD3ζ Lentiviral T cell   Inquiry
  Datasheet
CAR-LC363 Anti-GPC3×ASGR1 h(CD3ζ/CD28-41BB) Dual CAR, pCDCAR1 Human YP7 Mouse scFv (GPC3)-CD3ζ/scFv (ASGPR1)-CD28-41BB Lentiviral T cell   Inquiry
  Datasheet

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