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CASP8

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.

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  • TCR Viral Particles
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type Inquiry & Datasheet
CAR-CQ0109 Anti-CASP8 (CBXC-3111) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Primate CBXC-3111 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0110 Anti-CASP8 (CBXC-0083) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXC-0083 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0111 Anti-CASP8 (C15) h(41BB-CD3ζ) CAR, pCDCAR1 Human C15 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0112 Anti-CASP8 (CBXC-0084) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXC-0084 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0113 Anti-CASP8 (CBXC-2270) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXC-2270 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0114 Anti-CASP8 (CBXC-0082) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXC-0082 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0115 Anti-CASP8 (CBXC-1334) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXC-1334 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0116 Anti-CASP8 (FLICE 4-1-20) h(41BB-CD3ζ) CAR, pCDCAR1 Human FLICE 4-1-20 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3533 Anti-CASP8 (CBXC-3111) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Primate CBXC-3111 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3534 Anti-CASP8 (CBXC-0083) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-0083 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3535 Anti-CASP8 (C15) h(CD28-CD3ζ) CAR, pCDCAR1 Human C15 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3536 Anti-CASP8 (CBXC-0084) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-0084 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3537 Anti-CASP8 (CBXC-2270) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-2270 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3538 Anti-CASP8 (CBXC-0082) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-0082 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3539 Anti-CASP8 (CBXC-1334) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXC-1334 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3540 Anti-CASP8 (FLICE 4-1-20) h(CD28-CD3ζ) CAR, pCDCAR1 Human FLICE 4-1-20 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2661 Anti-CASP8 (CBFYC-0853) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYC-0853 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2662 Anti-CASP8 (CBFYC-0854) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBFYC-0854 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2663 Anti-CASP8 (CBFYC-0855) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYC-0855 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2664 Anti-CASP8 (CBFYC-0856) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBFYC-0856 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2665 Anti-CASP8 (CBFYC-0857) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBFYC-0857 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2666 Anti-CASP8 (CBFYC-0858) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYC-0858 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2667 Anti-CASP8 (CBFYC-0859) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYC-0859 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5914 Anti-CASP8 (CBFYC-0853) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYC-0853 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5915 Anti-CASP8 (CBFYC-0854) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBFYC-0854 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5916 Anti-CASP8 (CBFYC-0855) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYC-0855 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5917 Anti-CASP8 (CBFYC-0856) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBFYC-0856 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5918 Anti-CASP8 (CBFYC-0857) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBFYC-0857 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5919 Anti-CASP8 (CBFYC-0858) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYC-0858 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5920 Anti-CASP8 (CBFYC-0859) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYC-0859 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0084 Anti-CASP8 (CARL-1) h(41BB-CD3ζ) CAR, pCDCAR1 Human CARL-1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0085 Anti-CASP8 (CBWJC-0060) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJC-0060 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0086 Anti-CASP8 (CBWJC-0061) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBWJC-0061 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0087 Anti-CASP8 (CBWJC-0062) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJC-0062 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0088 Anti-CASP8 (CBWJC-0063) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJC-0063 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0089 Anti-CASP8 (CBWJC-0738) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJC-0738 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0090 Anti-CASP8 (CBWJC-0739) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJC-0739 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0091 Anti-CASP8 (CBWJC-0740) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJC-0740 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0092 Anti-CASP8 (C502S) h(41BB-CD3ζ) CAR, pCDCAR1 Human C502S Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ0093 Anti-CASP8 (CBWJC-0741) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJC-0741 scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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