EGFR

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases (RTK). These trans-membrane proteins are activated following binding with peptide growth factors of the EGF-family of proteins. Evidence suggests that the EGFR is involved in the pathogenesis and progression of different carcinoma types. The EGFR and EGF-like peptides are often over-expressed in human carcinomas. Mutations that lead to EGFR overexpression (known as upregulation) or overactivity have been associated with a number of cancers, including squamous-cell carcinoma of the lung (80% of cases), anal cancers, glioblastoma (50%) and epithelian tumors of the head and neck (80-100%).

EGFR Associated Disease
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  • CAR Viral Particles

  • DMAb

  • Protein

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  • TCR-Like CAR

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  • CAR mRNA

  • TCR-Like Antibody

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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP8476 A uniCAR [Anti-FITC CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Cetuximab)], a Switchable CAR System Breast cancer Lentiviral vector   Add to Cart   Datasheet
CAR-ZP8493 A uniCAR [Anti-CD16 CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Cetuximab)], a Switchable CAR System Breast cancer Lentiviral vector   Add to Cart   Datasheet
CAR-ZP8494 A uniCAR [Anti-CD16 CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Panitumumab)], a Switchable CAR System Breast cancer Lentiviral vector   Add to Cart   Datasheet
XS-0323-LX9 Anti-EGFR VHH(X3XH9) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH9 VHH-CD28-41BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX10 Anti-EGFR VHH(X3XH10) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH10 VHH-CD28-41BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX11 Anti-EGFR VHH(X3XH11) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH11 VHH-CD28-41BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX12 Anti-EGFR VHH(X3XH12) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH12 VHH-CD28-41BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX13 Anti-EGFR VHH(X3XH13) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH13 VHH-CD28-41BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX14 Anti-EGFR VHH(X3XH14) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH14 VHH-CD28-41BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX386 Anti-EGFR VHH(X3XH17) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH17 VHH-ICOS-4-1BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX387 Anti-EGFR VHH(X3XH18) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH18 VHH-ICOS-4-1BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX388 Anti-EGFR VHH(X3XH19) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH19 VHH-ICOS-4-1BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX389 Anti-EGFR VHH(X3XH20) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH20 VHH-ICOS-4-1BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX390 Anti-EGFR VHH(X3XH21) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH21 VHH-ICOS-4-1BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX391 Anti-EGFR VHH(X3XH22) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH22 VHH-ICOS-4-1BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX392 Anti-EGFR VHH(X3XH23) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH23 VHH-ICOS-4-1BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX393 Anti-EGFR VHH(X3XH24) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH24 VHH-ICOS-4-1BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX756 Anti-EGFR VHH(X3XH18) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector Human X3XH18 VHH-CD28-OX40-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX757 Anti-EGFR VHH(X3XH19) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector Human X3XH19 VHH-CD28-OX40-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX758 Anti-EGFR VHH(X3XH20) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector Human X3XH20 VHH-CD28-OX40-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX759 Anti-EGFR VHH(X3XH21) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector Human X3XH21 VHH-CD28-OX40-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX760 Anti-EGFR VHH(X3XH22) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector Human X3XH22 VHH-CD28-OX40-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX761 Anti-EGFR VHH(X3XH23) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector Human X3XH23 VHH-CD28-OX40-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
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