Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsThe advent of Chimeric Antigen Receptor T-cell (CAR-T) therapies has revolutionized the field of oncology, providing new avenues for treating various forms of cancer. Our 20 years of experience in the biotechnology sector have equipped us with the expertise and technological capabilities to support the entire lifecycle of CAR-T products, from early development to commercialization.
EXPLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsGet a real taste and understanding of the business and culture of one of the world's great research-based cellular and gene therapy discovery and development companies.
EXPLORE MOREAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases (RTK). These trans-membrane proteins are activated following binding with peptide growth factors of the EGF-family of proteins. Evidence suggests that the EGFR is involved in the pathogenesis and progression of different carcinoma types. The EGFR and EGF-like peptides are often over-expressed in human carcinomas. Mutations that lead to EGFR overexpression (known as upregulation) or overactivity have been associated with a number of cancers, including squamous-cell carcinoma of the lung (80% of cases), anal cancers, glioblastoma (50%) and epithelian tumors of the head and neck (80-100%).
Loading...
| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| CAR-ZP8476 | A uniCAR [Anti-FITC CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Cetuximab)], a Switchable CAR System | Breast cancer | Lentiviral vector | ||||||
| CAR-ZP8493 | A uniCAR [Anti-CD16 CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Cetuximab)], a Switchable CAR System | Breast cancer | Lentiviral vector | ||||||
| CAR-ZP8494 | A uniCAR [Anti-CD16 CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Panitumumab)], a Switchable CAR System | Breast cancer | Lentiviral vector | ||||||
| CAR-YF793 | Anti-EGFR (C225-M) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | C225-M | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF794 | Anti-EGFR (hICR62) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | hICR62 | Humanized | scFv-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF844 | Anti-EGFR (225) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | 225 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF846 | Anti-EGFR (ICR62) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | ICR62 | Humanized | scFv-CD28-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF847 | Anti-EGFR (GA201) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | GA201 | Humanized | scFv-CD28-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF848 | Anti-EGFR (Necitumumab) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | Necitumumab | Human | scFv-CD28-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF849 | Anti-EGFR (C225-H) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | C225-H | Mouse | scFv-CD28-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF850 | Anti-EGFR (C225-M) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | C225-M | Mouse | scFv-CD28-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF851 | Anti-EGFR (hICR62) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | hICR62 | Humanized | scFv-CD28-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF901 | Anti-EGFR (225) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | 225 | Mouse | scFv-CD28-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF904 | Anti-EGFR (ICR62) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 | Human | ICR62 | Humanized | scFv-CD28-OX40-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF905 | Anti-EGFR (GA201) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 | Human | GA201 | Humanized | scFv-CD28-OX40-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF906 | Anti-EGFR (Necitumumab) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 | Human | Necitumumab | Human | scFv-CD28-OX40-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF907 | Anti-EGFR (C225-H) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 | Human | C225-H | Mouse | scFv-CD28-OX40-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF908 | Anti-EGFR (C225-M) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 | Human | C225-M | Mouse | scFv-CD28-OX40-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF909 | Anti-EGFR (hICR62) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 | Human | hICR62 | Humanized | scFv-CD28-OX40-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF959 | Anti-EGFR (225) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 | Human | 225 | Mouse | scFv-CD28-OX40-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-SB-LX0203 | Anti-EGFR (Modotuximab) h(CD28-CD3ζ) CAR, pSBCAR1 | Human | Modotuximab | Mouse | scFv-CD28-CD3ζ | Sleeping Beauty (SB) transposon | T cell | ||
| CAR-SB-LX0204 | Anti-EGFR (Cetuximab) h(CD28-CD3ζ) CAR, pSBCAR1 | Human | Cetuximab | Mouse | scFv-CD28-CD3ζ | Sleeping Beauty (SB) transposon | T cell | ||
| CAR-SB-LX0205 | Anti-EGFR (Matuzumab) h(CD28-CD3ζ) CAR, pSBCAR1 | Human | Matuzumab | Mouse | scFv-CD28-CD3ζ | Sleeping Beauty (SB) transposon | T cell |
NEWSLETTER
The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders
LEARN MORE NEWSLETTER
NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
LEARN MORE SOLUTION
NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
LEARN MORE NOVEL TECHNOLOGY
NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
LEARN MORE SOLUTION
