EGFR

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases (RTK). These trans-membrane proteins are activated following binding with peptide growth factors of the EGF-family of proteins. Evidence suggests that the EGFR is involved in the pathogenesis and progression of different carcinoma types. The EGFR and EGF-like peptides are often over-expressed in human carcinomas. Mutations that lead to EGFR overexpression (known as upregulation) or overactivity have been associated with a number of cancers, including squamous-cell carcinoma of the lung (80% of cases), anal cancers, glioblastoma (50%) and epithelian tumors of the head and neck (80-100%).

EGFR Associated Disease
  • CAR Vector Products

  • AbTCR Vector Products

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  • CAR Viral Particles

  • DMAb

  • Protein

  • TriCAR Vector Products

  • TCR-Like CAR

  • CAR-MA Vector Products

  • CAR-MA Cell Products

  • CAR Animal Cells

  • CAR mRNA

  • TCR-Like Antibody

  • Off-shelf CAR-NK (vNK-92) Cell Product

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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YF125 Anti-EGFR (CBL-YF042) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF042 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF126 Anti-EGFR (CBL-YF042) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF042 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP154 Anti-EGFR (425) h(CD28-CD3ζ) CAR, pCDCAR1 Human 425 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP155 Anti-EGFR (425) h(41BB-CD3ζ) CAR, pCDCAR1 Human 425 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP224 Anti-EGFR (DL06) h(CD28-CD3ζ) CAR, pCDCAR1 Human DL06 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP225 Anti-EGFR (DL06) h(41BB-CD3ζ) CAR, pCDCAR1 Human DL06 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6554 Anti-EGFR (111.6) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse 111.6 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6555 Anti-EGFR (13G8) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse 13G8 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6556 Anti-EGFR (30H45L48) h(41BB-CD3ζ) CAR, pCDCAR1 Human 30H45L48 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6557 Anti-EGFR (31G7) h(41BB-CD3ζ) CAR, pCDCAR1 Human 31G7 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6558 Anti-EGFR (3H2093) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3H2093 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6559 Anti-EGFR (3H2094) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3H2094 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6560 Anti-EGFR (423103) h(41BB-CD3ζ) CAR, pCDCAR1 Human 423103 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6561 Anti-EGFR (5E10D3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 5E10D3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6601 Anti-EGFR (CBFYE-0549) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBFYE-0549 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6602 Anti-EGFR (CBFYE-0550) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0550 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6603 Anti-EGFR (CBFYE-0551) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYE-0551 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6604 Anti-EGFR (CBFYE-0552) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0552 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6605 Anti-EGFR (CBFYE-0553) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0553 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6606 Anti-EGFR (CBFYE-0554) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0554 Sheep scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8476 A uniCAR [Anti-FITC CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Cetuximab)], a Switchable CAR System Breast cancer Lentiviral vector   Add to Cart   Datasheet
CAR-ZP8493 A uniCAR [Anti-CD16 CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Cetuximab)], a Switchable CAR System Breast cancer Lentiviral vector   Add to Cart   Datasheet
CAR-ZP8494 A uniCAR [Anti-CD16 CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Panitumumab)], a Switchable CAR System Breast cancer Lentiviral vector   Add to Cart   Datasheet
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