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EGFR

The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases (RTK). These trans-membrane proteins are activated following binding with peptide growth factors of the EGF-family of proteins. Evidence suggests that the EGFR is involved in the pathogenesis and progression of different carcinoma types. The EGFR and EGF-like peptides are often over-expressed in human carcinomas. Mutations that lead to EGFR overexpression (known as upregulation) or overactivity have been associated with a number of cancers, including squamous-cell carcinoma of the lung (80% of cases), anal cancers, glioblastoma (50%) and epithelian tumors of the head and neck (80-100%).

Associated Disease
  • CAR Vector Products
  • CAR Viral Particles
  • DMAb
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-WFY6554 Anti-EGFR (111.6) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse 111.6 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6555 Anti-EGFR (13G8) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse 13G8 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6578 Anti-EGFR (ICR61) h(41BB-CD3ζ) CAR, pCDCAR1 ICR61 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6579 Anti-EGFR (M9020201) h(41BB-CD3ζ) CAR, pCDCAR1 M9020201 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6556 Anti-EGFR (30H45L48) h(41BB-CD3ζ) CAR, pCDCAR1 Human 30H45L48 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6557 Anti-EGFR (31G7) h(41BB-CD3ζ) CAR, pCDCAR1 Human 31G7 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6558 Anti-EGFR (3H2093) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3H2093 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6559 Anti-EGFR (3H2094) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3H2094 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6580 Anti-EGFR (Matuzumab) h(41BB-CD3ζ) CAR, pCDCAR1 Human Matuzumab Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6581 Anti-EGFR (me1B3) h(41BB-CD3ζ) CAR, pCDCAR1 Human me1B3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6560 Anti-EGFR (423103) h(41BB-CD3ζ) CAR, pCDCAR1 Human 423103 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6561 Anti-EGFR (5E10D3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 5E10D3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6633 Anti-EGFR (CBFYE-0581) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0581 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6634 Anti-EGFR (CBFYE-0582) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0582 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6635 Anti-EGFR (CBFYE-0583) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0583 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6636 Anti-EGFR (CBFYE-0584) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBFYE-0584 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6562 Anti-EGFR (5E10-G10-E11) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Monkey 5E10-G10-E11 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6563 Anti-EGFR (5G9B5) h(41BB-CD3ζ) CAR, pCDCAR1 Human 5G9B5 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6582 Anti-EGFR (MM0256-5S21) h(41BB-CD3ζ) CAR, pCDCAR1 Human MM0256-5S21 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6583 Anti-EGFR (R19/48MIX) h(41BB-CD3ζ) CAR, pCDCAR1 Human R19/48MIX Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6564 Anti-EGFR (688CT33.1.3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 688CT33.1.3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6565 Anti-EGFR (7A6F12) h(41BB-CD3ζ) CAR, pCDCAR1 Human 7A6F12 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6637 Anti-EGFR (CBFYE-0585) h(41BB-CD3ζ) CAR, pCDCAR1 Rat CBFYE-0585 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6638 Anti-EGFR (CBFYE-0586) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0586 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6639 Anti-EGFR (CBFYE-0587) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Rat, Mouse CBFYE-0587 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6640 Anti-EGFR (CBFYE-0588) h(41BB-CD3ζ) CAR, pCDCAR1 D. melanogaster CBFYE-0588 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6566 Anti-EGFR (AT2H8) h(41BB-CD3ζ) CAR, pCDCAR1 Human AT2H8 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6567 Anti-EGFR (D38B1) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Monkey D38B1 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6584 Anti-EGFR (REA688) h(41BB-CD3ζ) CAR, pCDCAR1 Human REA688 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6585 Anti-EGFR (SB41a) h(41BB-CD3ζ) CAR, pCDCAR1 Human SB41a Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6641 Anti-EGFR (CBFYE-0589) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBFYE-0589 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6642 Anti-EGFR (CBFYE-0590) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0590 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6643 Anti-EGFR (CBFYE-0591) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYE-0591 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6644 Anti-EGFR (CBFYE-0592) h(41BB-CD3ζ) CAR, pCDCAR1 Dog, Human, Mouse CBFYE-0592 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6645 Anti-EGFR (CBFYE-0593) h(41BB-CD3ζ) CAR, pCDCAR1 Dog, Human, Mouse, Rat CBFYE-0593 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6646 Anti-EGFR (CBFYE-0594) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0594 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6647 Anti-EGFR (CBFYE-0595) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0595 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6648 Anti-EGFR (CBFYE-0596) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0596 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6649 Anti-EGFR (CBFYE-0597) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYE-0597 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6650 Anti-EGFR (CBFYE-0598) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0598 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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