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EGFR

The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases (RTK). These trans-membrane proteins are activated following binding with peptide growth factors of the EGF-family of proteins. Evidence suggests that the EGFR is involved in the pathogenesis and progression of different carcinoma types. The EGFR and EGF-like peptides are often over-expressed in human carcinomas. Mutations that lead to EGFR overexpression (known as upregulation) or overactivity have been associated with a number of cancers, including squamous-cell carcinoma of the lung (80% of cases), anal cancers, glioblastoma (50%) and epithelian tumors of the head and neck (80-100%).

Associated Disease
  • CAR Vector Products
  • CAR Viral Particles
  • CAR Cell Products
  • DMAb
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type Inquiry & Datasheet
CAR-WFY6556 Anti-EGFR (30H45L48) h(41BB-CD3ζ) CAR, pCDCAR1 Human 30H45L48 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7358 Anti-EGFR (423103) h(CD28-CD3ζ) CAR, pCDCAR1 Human 423103 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7359 Anti-EGFR (5E10D3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5E10D3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7360 Anti-EGFR (5E10-G10-E11) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Monkey 5E10-G10-E11 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7361 Anti-EGFR (5G9B5) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5G9B5 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7362 Anti-EGFR (688CT33.1.3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 688CT33.1.3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7363 Anti-EGFR (7A6F12) h(CD28-CD3ζ) CAR, pCDCAR1 Human 7A6F12 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7364 Anti-EGFR (AT2H8) h(CD28-CD3ζ) CAR, pCDCAR1 Human AT2H8 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7365 Anti-EGFR (D38B1) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Monkey D38B1 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7366 Anti-EGFR (DH8.3) h(CD28-CD3ζ) CAR, pCDCAR1 Human DH8.3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7367 Anti-EGFR (EGFR.1) h(CD28-CD3ζ) CAR, pCDCAR1 Human EGFR.1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7368 Anti-EGFR (EGFR1) h(CD28-CD3ζ) CAR, pCDCAR1 Human EGFR1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7369 Anti-EGFR (EP38Y) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human EP38Y Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7370 Anti-EGFR (ERB7-1) h(CD28-CD3ζ) CAR, pCDCAR1 Human ERB7-1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7371 Anti-EGFR (GFR/1667) h(CD28-CD3ζ) CAR, pCDCAR1 Human GFR/1667 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7372 Anti-EGFR (GFR1195) h(CD28-CD3ζ) CAR, pCDCAR1 Human GFR1195 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7373 Anti-EGFR (GFR450) h(CD28-CD3ζ) CAR, pCDCAR1 Human GFR450 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7374 Anti-EGFR (GT461) h(CD28-CD3ζ) CAR, pCDCAR1 Human GT461 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7375 Anti-EGFR (H9B4) h(CD28-CD3ζ) CAR, pCDCAR1 Human H9B4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7376 Anti-EGFR (ICR61) h(CD28-CD3ζ) CAR, pCDCAR1 ICR61 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7377 Anti-EGFR (M9020201) h(CD28-CD3ζ) CAR, pCDCAR1 M9020201 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7394 Anti-EGFR (CBFYE-0122) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0122 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7395 Anti-EGFR (CBFYE-0240) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0240 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7396 Anti-EGFR (CBFYE-0546) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBFYE-0546 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7397 Anti-EGFR (CBFYE-0547) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0547 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7398 Anti-EGFR (CBFYE-0548) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0548 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7399 Anti-EGFR (CBFYE-0549) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBFYE-0549 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7400 Anti-EGFR (CBFYE-0550) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0550 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7401 Anti-EGFR (CBFYE-0551) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYE-0551 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7402 Anti-EGFR (CBFYE-0552) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0552 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7403 Anti-EGFR (CBFYE-0553) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0553 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7404 Anti-EGFR (CBFYE-0554) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0554 Sheep scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7405 Anti-EGFR (CBFYE-0555) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBFYE-0555 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7406 Anti-EGFR (CBFYE-0556) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0556 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7407 Anti-EGFR (CBFYE-0557) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0557 Sheep scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7408 Anti-EGFR (CBFYE-0558) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0558 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7409 Anti-EGFR (CBFYE-0559) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Dog, Pig, Rat CBFYE-0559 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7410 Anti-EGFR (CBFYE-0560) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0560 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7411 Anti-EGFR (CBFYE-0561) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0561 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7412 Anti-EGFR (CBFYE-0562) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0562 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet

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