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EGFR

The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases (RTK). These trans-membrane proteins are activated following binding with peptide growth factors of the EGF-family of proteins. Evidence suggests that the EGFR is involved in the pathogenesis and progression of different carcinoma types. The EGFR and EGF-like peptides are often over-expressed in human carcinomas. Mutations that lead to EGFR overexpression (known as upregulation) or overactivity have been associated with a number of cancers, including squamous-cell carcinoma of the lung (80% of cases), anal cancers, glioblastoma (50%) and epithelian tumors of the head and neck (80-100%).

Associated Disease
  • CAR Vector Products
  • CAR Viral Particles
  • CAR Cell Products
  • DMAb
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type Inquiry & Datasheet
CAR-ZP8078 Anti-EGFR (P3X) h(CD28-CD3ζ) CAR, pCDCAR1 Human P3X Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8079 Anti-EGFR (P3X) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human P3X Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8080 Anti-EGFR (D1P9C) h(CD28-CD3ζ) CAR, pCDCAR1 Human D1P9C Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8081 Anti-EGFR (D1P9C) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human D1P9C Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8082 Anti-EGFR (15F8) h(CD28-CD3ζ) CAR, pCDCAR1 Human 15F8 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8087 Anti-EGFR (L858R) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human L858R Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8088 Anti-EGFR (1F4) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1F4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8089 Anti-EGFR (1F4) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 1F4 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8090 Anti-EGFR (D1D4J) h(CD28-CD3ζ) CAR, pCDCAR1 Human D1D4J Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8832 Anti-EGFR (BA0185) h(CD28-CD3ζ) mRNA CAR, pcDCAR1 EBV BA0185 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8833 Anti-EGFR (BA0185) h(4-1BB-CD3ζ) mRNA CAR, pcDCAR1 EBV BA0185 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8476 Anti-EGFR (Cetuximab) CAR Adaptors (modCAR TagFITC) Human Cetuximab Mouse anti-FITC-CD28 TM/4-1BB/CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8479 Anti-EGFR (7C12) CAR Adaptors (modCAR TagE5B9) Human 7C12 Camelidnanobody anti-E5B9-CD28/CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8493 Anti-EGFR (Cetuximab) CAR Adaptors (modCAR Tag) Human Cetuximab Mouse anti-CD16 (FCGR3A) 48H and V158 variant-CD 28TM/CD28ICD/CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8494 Anti-EGFR (Panitumumab) CAR Adaptors (modCAR Tag) Human Panitumumab Mouse anti-CD16 (FCGR3A) 48H and V158 variant-CD 28TM/CD28ICD/CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF675 Anti-EGFR (ICR62) h(CD3ζ) CAR, pCDCAR1 Human ICR62 Humanized scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF676 Anti-EGFR (GA201) h(CD3ζ) CAR, pCDCAR1 Human GA201 Humanized scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF677 Anti-EGFR (Necitumumab) h(CD3ζ) CAR, pCDCAR1 Human Necitumumab Human scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF678 Anti-EGFR (C225-H) h(CD3ζ) CAR, pCDCAR1 Human C225-H Mouse scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF679 Anti-EGFR (C225-M) h(CD3ζ) CAR, pCDCAR1 Human C225-M Mouse scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF680 Anti-EGFR (hICR62) h(CD3ζ) CAR, pCDCAR1 Human hICR62 Humanized scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF730 Anti-EGFR (225) h(CD3ζ) CAR, pCDCAR1 Human 225 Mouse scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF734 Anti-EGFR (ICR62) h(CD28-CD3ζ) CAR, pCDCAR1 Human ICR62 Humanized scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF735 Anti-EGFR (GA201) h(CD28-CD3ζ) CAR, pCDCAR1 Human GA201 Humanized scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF736 Anti-EGFR (Necitumumab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Necitumumab Human scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF737 Anti-EGFR (C225-H) h(CD28-CD3ζ) CAR, pCDCAR1 Human C225-H Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF738 Anti-EGFR (C225-M) h(CD28-CD3ζ) CAR, pCDCAR1 Human C225-M Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF739 Anti-EGFR (hICR62) h(CD28-CD3ζ) CAR, pCDCAR1 Human hICR62 Humanized scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF789 Anti-EGFR (ICR62) h(41BB-CD3ζ) CAR, pCDCAR1 Human ICR62 Humanized scFv-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF790 Anti-EGFR (GA201) h(41BB-CD3ζ) CAR, pCDCAR1 Human GA201 Humanized scFv-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF791 Anti-EGFR (Necitumumab) h(41BB-CD3ζ) CAR, pCDCAR1 Human Necitumumab Human scFv-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF792 Anti-EGFR (C225-H) h(41BB-CD3ζ) CAR, pCDCAR1 Human C225-H Mouse scFv-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF793 Anti-EGFR (C225-M) h(41BB-CD3ζ) CAR, pCDCAR1 Human C225-M Mouse scFv-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF794 Anti-EGFR (hICR62) h(41BB-CD3ζ) CAR, pCDCAR1 Human hICR62 Humanized scFv-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF846 Anti-EGFR (ICR62) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human ICR62 Humanized scFv-CD28-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF847 Anti-EGFR (GA201) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human GA201 Humanized scFv-CD28-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF848 Anti-EGFR (Necitumumab) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human Necitumumab Human scFv-CD28-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF849 Anti-EGFR (C225-H) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human C225-H Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF850 Anti-EGFR (C225-M) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human C225-M Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF959 Anti-EGFR (225) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human 225 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet

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