GPC3

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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Associated Disease
  • Hepatocellular carcinoma
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0822-LX162 Anti-GPC3 (X8X162) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X162 Human scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX163 Anti-GPC3 (X8X163) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X163 Humanized scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX164 Anti-GPC3 (X8X164) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X164 Human scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX165 Anti-GPC3 (X8X165) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X165 Human scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX166 Anti-GPC3 (X8X166) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X166 Human scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX167 Anti-GPC3 (X8X167) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X167 Humanized scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX168 Anti-GPC3 (X8X168) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X168 Humanized scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX169 Anti-GPC3 (X8X169) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X169 Human scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX170 Anti-GPC3 (X8X170) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X170 Human scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX345 Anti-GPC3 (X8X158) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X158 Human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX346 Anti-GPC3 (X8X159) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X159 Human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX347 Anti-GPC3 (X8X160) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X160 Humanized scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX348 Anti-GPC3 (X8X161) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X161 Human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX530 Anti-GPC3 (X8X156) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X156 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX531 Anti-GPC3 (X8X157) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X157 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX532 Anti-GPC3 (X8X158) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X158 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX533 Anti-GPC3 (X8X159) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X159 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX534 Anti-GPC3 (X8X160) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X160 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX535 Anti-GPC3 (X8X161) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X161 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX536 Anti-GPC3 (X8X162) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X162 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0823-LX63 Anti-hGPC3 (Ab) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human Ab Adenoviral vectors   Add to Cart   Datasheet
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