GPC3

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Associated Disease
  • Hepatocellular carcinoma
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1122-YF464 Anti-GPC3 KIR CAR (scFv-KIR2DS2-DAP12, XW-464), pCDCAR1 Human XW-464 Human scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF1395 Anti-GPC3 TCR-ABR (scFv-TCRα, XW-475) CAR Plasmid, pCDCAR1 Human XW-475 Mouse scFv-TCRα Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF1396 Anti-GPC3 TCR-ABR (scFv-TCRα, XW-476) CAR Plasmid, pCDCAR1 Human XW-476 Mouse scFv-TCRα Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF1397 Anti-GPC3 TCR-ABR (scFv-TCRα, GC33) CAR Plasmid, pCDCAR1 Human GC33 Mouse scFv-TCRα Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF1398 Anti-GPC3 TCR-ABR (scFv-TCRα, XW-478) CAR Plasmid, pCDCAR1 Human XW-478 Mouse scFv-TCRα Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF1399 Anti-GPC3 TCR-ABR (scFv-TCRα, XW-479) CAR Plasmid, pCDCAR1 Human XW-479 Mouse scFv-TCRα Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2304 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-464) CAR Plasmid, pCDCAR1 Human XW-464 Human scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2305 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-465) CAR Plasmid, pCDCAR1 Human XW-465 Human scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2306 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-466) CAR Plasmid, pCDCAR1 Human XW-466 Human scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2310 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-470) CAR Plasmid, pCDCAR1 Human XW-470 Human scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2311 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-471) CAR Plasmid, pCDCAR1 Human XW-471 Human scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2312 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-472) CAR Plasmid, pCDCAR1 Human XW-472 Human scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2313 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-473) CAR Plasmid, pCDCAR1 Human XW-473 Human scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2314 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-474) CAR Plasmid, pCDCAR1 Mouse XW-474 Human scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2315 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-475) CAR Plasmid, pCDCAR1 Human XW-475 Mouse scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2316 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-476) CAR Plasmid, pCDCAR1 Human XW-476 Mouse scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2317 Anti-GPC3 TCR-ABR (scFv-TCRβ, GC33) CAR Plasmid, pCDCAR1 Human GC33 Mouse scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2318 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-478) CAR Plasmid, pCDCAR1 Human XW-478 Mouse scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2319 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-479) CAR Plasmid, pCDCAR1 Human XW-479 Mouse scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF2320 Anti-GPC3 TCR-ABR (scFv-TCRβ, XW-480) CAR Plasmid, pCDCAR1 Human XW-480 Mouse scFv-TCRβ Lentiviral vector T Cell   Add to Cart   Datasheet
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