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GPC3

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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Associated Disease
  • Hepatocellular carcinoma

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  • CAR mRNA

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  • Target Species:
  • Antibody Clone:
  • Antibody Host:
  • Receptor Construction:
  • Vector Type:
  • Targeting Cell Type:
  • CAR Vector Type:
CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0722-YF160 TS-Fluc Anti-Human GPC3 scFv (GC33) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human GC33 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF400 TS-NKG2DL Anti-hCD3 and Anti-Human GPC3 scFv (GC33) CD28-CD3ζ CAR, pCDCAR1 Human GC33 Mouse 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX145 Anti-GPC3 (X8X145) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X145 Humanized scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX146 Anti-GPC3 (X8X146) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X146 Humanized scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX147 Anti-GPC3 (X8X147) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X8X147 Humanized scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX323 Anti-GPC3 (X8X136) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X136 Human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX324 Anti-GPC3 (X8X137) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X137 Human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX336 Anti-GPC3 (X8X149) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X149 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX337 Anti-GPC3 (X8X150) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X150 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX338 Anti-GPC3 (X8X151) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X151 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX339 Anti-GPC3 (X8X152) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X152 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX340 Anti-GPC3 (X8X153) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X8X153 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX506 Anti-GPC3 (X8X132) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X132 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX507 Anti-GPC3 (X8X133) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X133 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX508 Anti-GPC3 (X8X134) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X134 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX522 Anti-GPC3 (X8X148) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X148 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX524 Anti-GPC3 (X8X150) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X150 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX525 Anti-GPC3 (X8X151) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X151 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX526 Anti-GPC3 (X8X152) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X152 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX527 Anti-GPC3 (X8X153) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X153 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0823-LX63 Anti-hGPC3 (Ab) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human Ab Adenoviral vectors   Add to Cart   Datasheet
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