GPC3

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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Associated Disease
  • Hepatocellular carcinoma
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY6802 Anti-GPC3 (CBFYH-2978) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2978 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6803 Anti-GPC3 (CBFYH-2979) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2979 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6804 Anti-GPC3 (CBFYH-2980) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2980 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY6805 Anti-GPC3 (CBFYH-0434) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-0434 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7557 Anti-GPC3 (CBFYH-0436) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-0436 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7564 Anti-GPC3 (CBFYH-0435) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-0435 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7600 Anti-GPC3 (CBFYH-2978) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-2978 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7601 Anti-GPC3 (CBFYH-2979) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-2979 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7602 Anti-GPC3 (CBFYH-2980) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-2980 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7603 Anti-GPC3 (CBFYH-0434) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-0434 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP2988 Anti-GPC3 (2G9) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2G9 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP2989 Anti-GPC3 (2G9) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2G9 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP2990 Anti-GPC3 (CAR-ZP2990) h(CD28-CD3ζ) CAR, pCDCAR1 Human CAR-ZP2990 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP2991 Anti-GPC3 (CAR-ZP2991) h(41BB-CD3ζ) CAR, pCDCAR1 Human CAR-ZP2991 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP2992 Anti-GPC3 (3D8) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3D8 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP3025 Anti-GPC3 (GT30) h(41BB-CD3ζ) CAR, pCDCAR1 Human GT30 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP3026 Anti-GPC3 (9C2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 9C2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP3027 Anti-GPC3 (9C2) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9C2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP3028 Anti-GPC3 (2C12) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2C12 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP3029 Anti-GPC3 (2C12) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2C12 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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