GPC3

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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Associated Disease
  • Hepatocellular carcinoma
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  • Target Species:
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0822-YF10220 TS-IL15 SA Anti-Human GPC3 scFv (XW-471) 41BB-CD3ζ CAR, pCDCAR1 Human XW-471 Human 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10221 TS-IL15 SA Anti-Human GPC3 scFv (XW-472) 41BB-CD3ζ CAR, pCDCAR1 Human XW-472 Human 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10222 TS-IL15 SA Anti-Human GPC3 scFv (XW-473) 41BB-CD3ζ CAR, pCDCAR1 Human XW-473 Human 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10223 TS-IL15 SA Anti-Mouse GPC3 scFv (XW-474) 41BB-CD3ζ CAR, pCDCAR1 Mouse XW-474 Human 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10224 TS-IL15 SA Anti-Human GPC3 scFv (XW-475) 41BB-CD3ζ CAR, pCDCAR1 Human XW-475 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10225 TS-IL15 SA Anti-Human GPC3 scFv (XW-476) 41BB-CD3ζ CAR, pCDCAR1 Human XW-476 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10226 TS-IL15 SA Anti-Human GPC3 scFv (XW-477) 41BB-CD3ζ CAR, pCDCAR1 Human XW-477 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10227 TS-IL15 SA Anti-Human GPC3 scFv (XW-478) 41BB-CD3ζ CAR, pCDCAR1 Human XW-478 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10228 TS-IL15 SA Anti-Human GPC3 scFv (XW-479) 41BB-CD3ζ CAR, pCDCAR1 Human XW-479 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10229 TS-IL15 SA Anti-Human GPC3 scFv (XW-480) 41BB-CD3ζ CAR, pCDCAR1 Human XW-480 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10625 TS-IL15 SA Anti-Human GPC3 scFv (XW-467) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-467 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10626 TS-IL15 SA Anti-Human GPC3 scFv (XW-468) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-468 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10627 TS-IL15 SA Anti-Human GPC3 scFv (XW-469) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-469 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10628 TS-IL15 SA Anti-Human GPC3 scFv (XW-470) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-470 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10629 TS-IL15 SA Anti-Human GPC3 scFv (XW-471) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-471 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10630 TS-IL15 SA Anti-Human GPC3 scFv (XW-472) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-472 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10631 TS-IL15 SA Anti-Human GPC3 scFv (XW-473) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-473 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10632 TS-IL15 SA Anti-Mouse GPC3 scFv (XW-474) CD28-41BB-CD3ζ CAR, pCDCAR1 Mouse XW-474 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10633 TS-IL15 SA Anti-Human GPC3 scFv (XW-475) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-475 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10634 TS-IL15 SA Anti-Human GPC3 scFv (XW-476) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-476 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
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