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GPC3

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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Associated Disease
  • Hepatocellular carcinoma

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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0822-LX513 Anti-GPC3 (X8X139) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X139 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX514 Anti-GPC3 (X8X140) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X140 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX515 Anti-GPC3 (X8X141) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X141 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX516 Anti-GPC3 (X8X142) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X142 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX517 Anti-GPC3 (X8X143) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X143 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX518 Anti-GPC3 (X8X144) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X144 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX519 Anti-GPC3 (X8X145) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X145 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX520 Anti-GPC3 (X8X146) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X146 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX521 Anti-GPC3 (X8X147) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X147 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX522 Anti-GPC3 (X8X148) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X148 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX523 Anti-GPC3 (X8X149) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X149 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX524 Anti-GPC3 (X8X150) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X150 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX525 Anti-GPC3 (X8X151) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X151 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX526 Anti-GPC3 (X8X152) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X152 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX527 Anti-GPC3 (X8X153) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X153 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX528 Anti-GPC3 (X8X154) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X154 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX529 Anti-GPC3 (X8X155) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X155 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX530 Anti-GPC3 (X8X156) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X156 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX531 Anti-GPC3 (X8X157) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X157 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-LX532 Anti-GPC3 (X8X158) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X8X158 Human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0823-LX63 Anti-hGPC3 (Ab) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human Ab Adenoviral vectors   Add to Cart   Datasheet
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