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MYH11

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The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ7282 Anti-MYH11 (CBXS-4155) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-4155 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7285 Anti-MYH11 (CBXS-4906) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-4906 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7302 Anti-MYH11 (CBXS-1528) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-1528 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7316 Anti-MYH11 (ID8) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Rat, Rabbit, Cattle, Chicken, Guinea pig, Dog, Pig, Cat ID8 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7317 Anti-MYH11 (CBX-050) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBX-050 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7320 Anti-MYH11 (MS-13) h(CD28-CD3ζ) CAR, pCDCAR1 Human MS-13 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7321 Anti-MYH11 (MYH11/923) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Rat MYH11/923 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7323 Anti-MYH11 (SMM11-1) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Rat SMM11-1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7325 Anti-MYH11 (SPM201) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Rat, Rabbit, Cattle, Chicken, Guinea pig, Dog, Pig, Cat SPM201 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7762 Anti-MYH11 (CBXS-4155) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-4155 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7765 Anti-MYH11 (CBXS-4906) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBXS-4906 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7782 Anti-MYH11 (CBXS-1528) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBXS-1528 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7796 Anti-MYH11 (ID8) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human, Rat, Rabbit, Cattle, Chicken, Guinea pig, Dog, Pig, Cat ID8 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7797 Anti-MYH11 (CBX-050) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBX-050 Rat scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7800 Anti-MYH11 (MS-13) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human MS-13 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7801 Anti-MYH11 (MYH11/923) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human, Rat MYH11/923 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7803 Anti-MYH11 (SMM11-1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human, Rat SMM11-1 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7805 Anti-MYH11 (SPM201) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human, Rat, Rabbit, Cattle, Chicken, Guinea pig, Dog, Pig, Cat SPM201 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7065 Anti-MYH11 (CBFYM-0328) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Rat, Pig, Dog, Chicken, Cat, Guinea pig, Primate, Rabbit CBFYM-0328 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7066 Anti-MYH11 (CBFYM-0385) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Rat CBFYM-0385 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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