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STAU1

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Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ3124 Anti-STAU1 (CBXS-5598) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-5598 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3125 Anti-STAU1 (CBXS-1591) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-1591 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3126 Anti-STAU1 (CBXS-2769) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-2769 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3127 Anti-STAU1 (CBXS-3201) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-3201 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ6548 Anti-STAU1 (CBXS-5598) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-5598 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ6549 Anti-STAU1 (CBXS-1591) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-1591 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ6550 Anti-STAU1 (CBXS-2769) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-2769 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ6551 Anti-STAU1 (CBXS-3201) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-3201 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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