Bioactive Carbohydrates Screening Services

Carbohydrates play an essential role in human biology and disease development and are a relatively untapped source of bioactive compounds for use as pharmaceuticals. With industry-leading expertise and state-of-the-art single-use equipment, Creative Biolabs has pioneered the identification of cancer-associated carbohydrates.

Researchers have confirmed that carbohydrates from natural products possess wide-ranging beneficial therapeutic effects and health-promoting properties. With extensive experience in the field of bioactive carbohydrates, Creative Biolabs offers the most comprehensive services, including but not limited to the identification, characterization, and analysis of bioactive carbohydrates.

Bioactive Carbohydrates from Various Sources

• Seaweed polysaccharides

  According to their pigmentation, seaweeds are classified into brown (Phaeophyta), red (Rhodophyta), and green (Chlorophyta). The species that are industrially used belong to the divisions Phaeophyta and Rhodophyta. Bioactivities associated with seaweed polysaccharides include anti-viral, antimicrobial, anti-thrombotic, and antioxidant properties. Seaweed polysaccharides, such as alginate, carrageenan, laminarin, fucoidan, and agar are widely distributed in biomedical and biological applications, such as tissue engineering, wound healing, drug delivery, and biosensor due to their biocompatibility and availability.

• Fungal polysaccharides

  Fungal polysaccharides, derived from G. frondosa, L. edodes, oyster mushroom, as well as Flammulina, Ganoderma, Cordyceps, Coriolus, and Pleurotus, are demonstrated to have multiple bioactivities, including immunomodulating, anticancer, antimicrobial, hypocholesterolemic and hypoglycemic effects.

Fig.1 Potential uses of bioactive fungal polysaccharides. (Mohan, 2019)

• Bacterial polysaccharides

  Bacterial polysaccharides, including extracellular polysaccharides, loosely associated with bacterium, capsular polysaccharides, tightly bound to bacteria surface, and lipopolysaccharides, always anchored to the cell surface by lipid, are nontoxic natural biopolymers and provide extensive applications in pharmacology, nutraceutical, functional food, cosmeceutical, herbicides, and insecticides.

Research efforts concerning the use of bioactive carbohydrates are still considered under-exploited. However, bioactive carbohydrates from natural sources have found use in several biotechnological and pharmaceutical applications. Consequently, there is growing interest in further pursuing the potential bioactivities of diverse carbohydrates.

Bioactive Carbohydrates Screening Service at Creative Biolabs

Specific bioactivities such as modulating blood glucose, reducing serum cholesterol and insulin levels, fermentability in the gastrointestinal tract, anti-inflammatory, anticancer, immune regulatory, and anti-oxidant activities have been demonstrated by previous researches. Experienced in the study of bioactive carbohydrates and with a dedicated commitment to the scientific community, Creative Biolabs has perfected our technical pipelines in the identification of bioactive carbohydrates, including but not limited to:

• Identification of polysaccharides with anticancer activity
• Identification of glycans with antiviral activity
• Identification of polysaccharides with antibacterial activity
• Identification of polysaccharides with antioxidant activity

Scientists at Creative Biolabs are proficient at employing tailored strategies for the identification, purification, and downstream processing of bioactive carbohydrates. We would like to share our knowledge and passion for the identification of bioactive carbohydrates to facilitate our customers' research and project development. For more detailed information, please feel free to contact us or directly send us an inquiry.

Reference

1. Mohan, K.; et al. Potential uses of fungal polysaccharides as immunostimulants in fish and shrimp aquaculture: a review. Aquaculture. 2019, 500: 250-63.

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