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Equipped with world-leading technology platforms and professional scientific staff in carbohydrate research, Creative Biolabs is an ideal company to entrust with your project in the identification of polysaccharides with antibacterial activity. Through our high-throughput system, clients could accelerate their research with reducing project costs and timelines.
Antibiotic use increases significantly due to severe infections and bacterial pathogen resistance against drugs due to the uncontrolled use of antibiotics. The treatment of resistant pathogenic bacteria becomes more difficult, requires high costs, and causes adverse effects on the host, such as the occurrence of hypersensitivity and reduced profitable microbes in the gut. Decreased efficiency and pathogen resistance to antibiotics has necessitated the development of new alternative antibiotics.
The organisms from marine environment have been found possessing a vast array of new pharmaceutical compounds with novel activities. These new compounds may provide new drug leads to inhibit microbial pathogens currently developing resistance to conventional antibiotic therapies. In recent years, bacterial metabolites have gained significant importance in drug research. The study of natural products that exhibit antibacterial activity has long been showing significant biomedical value. Natural products isolated from marine organisms have served as a source of many drugs. For instance, marine algae are a source of raw materials that are widely used in the pharmaceutical, medical, food, and cosmetic industries. Polysaccharides (alginate, carrageen, and agar) derived from algae contain compounds with antibacterial activity and are used in medicine and pharmacy.
Fig.1 Antimicrobial activity of cell free culture supernatants of Lactobacillus isolates. (Davoodabadi, 2015)
As a leading specialist in the identification of carbohydrates with bioactive activity, Creative Biolabs excels at the discovery of polysaccharides with antibacterial activity. The antibacterial effectiveness against common pathogens, such as Listeria monocytogenes, Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Salmonella paratyphi, and Pseudomonas aeruginosa, can be investigated. The change of bacterial growth curve, electric conductivity, alkaline phosphatase (AKP), and β-galactosidase activity can be monitored, and the minimum inhibitory concentration (MIC) to pathogens can be measured.
Our comprehensive powerful platform, professional technical scientists, and abundant experience make us a perfect partner to help our clients in the identification of polysaccharides with antibacterial activity. For more detailed information, please feel free to contact us or directly send us an inquiry.