MetaVital™ Human Glutathione S-transferase theta-4 (GSTT4) ELISA Kit

CAT#: ITS-0326-WB39
Product Type: ELISA Kit
Species: Human
Target: Human Glutathione S-Transferase Theta-4 (GSTT4)
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively detects human GSTT4 protein levels in biological samples using a sensitive sandwich ELISA method.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Human Glutathione S-Transferase Theta-4 (GSTT4) ELISA Kit is a high-performance immunoassay designed for accurate quantification of GSTT4 in human biological samples. Utilizing a sandwich ELISA format with highly specific antibodies, this kit enables reliable detection of GSTT4 in serum, plasma, tissue extracts, and cell lysates, supporting studies of detoxification pathways, oxidative stress responses, and xenobiotic metabolism.
Features
Highly specific antibody pair enables accurate detection of human GSTT4 with minimal cross-reactivity, ensuring reliable quantification in complex biological matrices.
Sensitive sandwich ELISA format provides strong signal amplification and broad dynamic range for consistent measurement of GSTT4 concentrations.
Pre-optimized reagents and validated protocol simplify assay setup while supporting reproducible, high-throughput analysis across multiple experimental samples.
Suitable for diverse human biological samples including serum, plasma, tissue lysates, and cultured cell extracts for versatile experimental applications.
Process Relevance
Monitoring GSTT4 levels helps evaluate cellular detoxification capacity and oxidative stress responses during toxicological and metabolic studies.
Application Stage
Drug discovery, biomarker research, toxicology studies, and metabolic pathway investigations in human biological systems.
Applications
Quantitative detection of GSTT4 in human serum, plasma, cell lysates, and tissue extracts for oxidative stress analysis, detoxification research, biomarker discovery, ADME profiling studies, and pharmacological studies.
Target
Human Glutathione S-Transferase Theta-4 (GSTT4)
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Oxidative stress biology, pharmacokinetics (ADME), xenobiotic metabolism, toxicology, pharmacology, biomarker discovery, metabolic disease research, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using endpoint absorbance detection in a sandwich ELISA assay.
Assay Range
0.156 ng/ml - 10 ng/ml
Species
Human
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glutathione S-transferases (GSTs) are a family of detoxification enzymes that protect cells against oxidative and chemical stress. GSTT4 belongs to the theta class of GSTs and participates in conjugating reduced glutathione to electrophilic substrates. This activity supports cellular defense mechanisms and contributes to the metabolism of environmental toxins and endogenous reactive molecules.
Pathways
GSTT4 functions within glutathione-dependent detoxification pathways, catalyzing the conjugation of glutathione to reactive intermediates generated during xenobiotic metabolism. It interacts functionally with glutathione biosynthesis systems and antioxidant defense networks to maintain intracellular redox balance and detoxification capacity.
For Research Use Only | Not For Clinical Use
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