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MemDX™ Antibody Discovery - Human CD133 (20-865) Membrane Protein, Partial, -His tag (Insect cell) (CAT#: MP1187F)

Datasheet
This membrane protein is Human CD133 (20-865). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD133
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 97.2 kDa. The protein migrates as 80-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gly 20 - His 865 (Accession # O43490-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • Baculovirus-Insect cells
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >80% as determined by SDS-PAGE.
  • Buffer
  • Delivered as bulk protein in a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 with glycerol as protectant.

Target

  • Target Protein
  • CD133
  • Full Name
  • prominin 1
  • Introduction
  • This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061; prominin-1; antigen AC133; hProminin; hematopoietic stem cell antigen; prominin-like protein 1

Case Studies

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