Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights
Struggling with antibody identity or uncertain hybridoma lineage? Get definitive answers now. Creative Biolabs cuts through the uncertainty, delivering precise sequence-level clarity fast. Engineer antibodies, verify clones, or recover lost sequences with confidence.
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Trusted expertise for precise sequence analysis
Several years of experience across species, isotypes, and sample types.
Accepting RNA, DNA, cells, protein, or even hybridoma supernatant.
From sequencing to expression and engineering — all under one roof.
Strict confidentiality and IP-safe workflows, always.
Precision Starts with Knowing Your Sequence
We begin with a detailed discussion to understand your goals, sample type (protein, cell line, supernatant), and the best-fit sequencing approach.
Depending on the sample, we apply optimized methods for antibody digestion (for de novo), RNA isolation (for hybridoma), or direct protein processing. All materials are QC-checked before sequencing.
We employ appropriate technologies — such as Database Assisted Shotgun Sequencing (DASS), LC-MS/MS, or NGS — based on the service type and input format.
Results include IMGT-annotated VH/VL sequences, CDRs, and optional expression-ready formats, all presented in a clear, publication-grade report.
Comprehensive solutions for antibody sequence analysis
Clients who have antibodies in purified form and are in need of gene information from those proteins can benefit from our de novo sequencing service. Our Database Assisted Shotgun Sequencing (DASS), which is our in-house developed proprietary platform based on cutting-edge MS and database matching, can deduce the accurate heavy and light chain amino acid sequences through this powerful mass-spectrometry based approach.
For clients with existing hybridoma cell lines, we offer a fully validated sequencing platform to recover and confirm antibody-encoding genes. Our process uses mRNA extraction, RT-PCR amplification of VH and VL regions, followed by Sanger or NGS sequencing.
We integrate multiple sequencing and analysis technologies for unmatched accuracy and flexibility
For high-throughput, full-chain profiling
For low-throughput, confirmatory or small-scale projects
Applied in De Novo recovery workflows
For mass spec-based de novo reconstruction using antibody-specific databases.
Download the infographic about our solutions for accurately identifying unknown antibody sequences directly from protein samples with our advanced De Novo sequencing platform.
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We routinely sequence antibodies from mouse, human, rabbit, rat, and camelid sources. For others, just consult with us — we’re flexible.
Yes — our DASS-based De Novo sequencing is designed exactly for this. As long as you can provide the required volume of purified antibody, we will try our best to recover full VH and VL sequences.
You’ll receive both. We provide the full annotated sequence report, IMGT and IgBLAST results, chain pairing info, and all associated raw data (FASTQ, chromatograms, spectra). This ensures transparency and reproducibility. We’re also happy to provide follow-up support to interpret the results or integrate them into your downstream workflow.
Yes, once the sequence is confirmed, our antibody engineering team can assist with humanization, affinity maturation, Fc region switching, or bispecific design. Many of our sequencing clients choose to bundle engineering services for a seamless transition into preclinical development.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
