Anti-LMP2 (AVFDRKSDAK) TCR, pMP71(TCR-L016)
The vector of anti-EBV T cell receptor (TCR) is constructed for the engineering of T cell to target EBV. The T cells are genetically modified through transduction with a retroviral vector expressing EBV-specific T cell receptor. And the vector product was designed for the treatment of infectious mononucleosis, Burkitt's lymphoma, Hodgkin's lymphoma,gastric cancer,nasopharyngeal carcinoma, multiple sclerosis, and lymphomatoid granulomatosis.
Details
Format
Cysteine-modified TCR
Targeting Diseases
Infectious mononucleosis, Burkitt's lymphoma, Hodgkin's lymphoma,gastric cancer,nasopharyngeal carcinoma, multiple sclerosis, and lymphomatoid granulomatosis.
Vector Type
retroviral vector
Target
Gene Name
EBNA3A nuclear protein
Synonyms
CT1.10; MAGE10; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Melanoma
Introduction
The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is a virus of the herpes family,
and is one of the most common viruses in humans.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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LymphomaViral InfectionOthersCarcinoma
Datasheet
