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Anti-LMP2 (AVFDRKSDAK) TCR, pMP71 (TCR-L016)

The vector of anti-EBV T cell receptor (TCR) is constructed for the engineering of T cell to target EBV. The T cells are genetically modified through transduction with a retroviral vector expressing EBV-specific T cell receptor. And the vector product was designed for the treatment of infectious mononucleosis, Burkitt's lymphoma, Hodgkin's lymphoma,gastric cancer,nasopharyngeal carcinoma, multiple sclerosis, and lymphomatoid granulomatosis.

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Details

  • Target
  • EBV
  • Target Species
  • EBV
  • Epitope
  • AVFDRKSDAK
  • Format
  • Cysteine-modified TCR
  • Allele
  • HLA- A11
  • Targeting Diseases
  • Infectious mononucleosis, Burkitt's lymphoma, Hodgkin's lymphoma,gastric cancer,nasopharyngeal carcinoma, multiple sclerosis, and lymphomatoid granulomatosis.
  • Vector Name
  • pMP71
  • Vector Length
  • 3817bp
  • Vector Type
  • retroviral vector
  • Host Species
  • Human

Target

  • Official Symbol
  • LMP2
  • Introduction
  • The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is a virus of the herpes family,
    and is one of the most common viruses in humans.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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All services and products are only for lab research use, not for any clinical diagnosis or treatment.

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