CD1D

This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.

Associated Disease
  • Cancer and autoimmune diseases

TCR Vector Products Product list:

Catalog Target Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Vector
Type
Epitope Format HLA Data
sheet
Price
TCR-L008 CD1D Human Human 6714-6688bp retroviral vector Cysteine-modified TCR HLA-A2 Inquiry
TCR-L008Z CD1D Human Human 8kb Lentiviral Cysteine-modified HLA-A2 Inquiry
TCR-L009 CD1D Mouse Mouse 6714-6688bp retroviral vector Non-modified TCR Inquiry
TCR-L009Z CD1d Mouse Mouse 8kb Lentiviral Non-modified Inquiry

TCR Viral Particles Product list:

Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Packaging
System
Epitope Format Titer Data
sheet
Price
VP-TCR-C028 Human Human Lentivirus Cysteine-modified TCR > 10⁷ IFU/ml Inquiry
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