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CD1D

This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.

Associated Disease
  • Cancer and autoimmune diseases
  • TCR Vector Products
  • TCR Viral Particles
CAT Product Name Target Species Antibody Clone Antibody Host Epitope HLA Vector Type  
TCR-L008 Human anti-CD1D T Cell Receptor[Cysteine-modified], pLXSN Human Human HLA-A2 retroviral vector   Inquiry
  Datasheet
TCR-L009 Mouse anti-CD1D T Cell Receptor, pLXSN Mouse Mouse retroviral vector   Inquiry
  Datasheet
TCR-L008Z Human anti-CD1D T cell receptor (Cysteine-modified), pCDTCR1 Human Human HLA-A2 Lentiviral   Inquiry
  Datasheet
TCR-L009Z Mouse anti-CD1d T cell receptor, pCDTCR1 Mouse Mouse Lentiviral   Inquiry
  Datasheet

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