CD37

Leukocyte antigen CD37 is a protein that in humans is encoded by the CD37 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

Associated Disease
  • Systemic lupus erythematosus (SLE)
  • Autoimmune disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-T-1-L333-2 T cell First G28-1 8kb Lentiviral scFv-CD28 Mouse Inquiry
CAR-T-1-L333-G T cell First G28-1 8kb Lentiviral scFv-FcεRIγ Mouse Inquiry
CAR-T-1-L333-Z T cell First G28-1 8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-T-2-L333-2G T cell Second G28-1 8kb Lentiviral scFv-CD28-FcεRIγ Mouse Inquiry
CAR-T-2-L333-2Z T cell Second G28-1 8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-2-L333-4G T cell Second G28-1 8kb Lentiviral scFv-CD4-FcεRIγ Mouse Inquiry
CAR-T-2-L333-4Z T cell Second G28-1 8kb Lentiviral scFv-CD4-CD3ζ Mouse Inquiry
CAR-T-2-L333-8Z T cell Second G28-1 8kb Lentiviral scFv-CD8-CD3ζ Mouse Inquiry
CAR-T-2-L333-BZ T cell Second G28-1 8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-2-L333-CZ T cell Second G28-1 8kb Lentiviral scFv-b2c-CD3ζ Mouse Inquiry
CAR-T-3-L333-2BZ T cell Third G28-1 8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-T-3-L333-2XZ T cell Third G28-1 8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC109 G28-1 Lentivirus First scFv (G28-1)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC110 G28-1 Lentivirus First scFv (G28-1)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC111 G28-1 Lentivirus First scFv (G28-1)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC112 G28-1 Lentivirus Second scFv (G28-1)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC113 G28-1 Lentivirus Second scFv (G28-1)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC114 G28-1 Lentivirus Second scFv (G28-1)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC115 G28-1 Lentivirus Second scFv (G28-1)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC116 G28-1 Lentivirus Second scFv (G28-1)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC117 G28-1 Lentivirus Second scFv (G28-1)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC118 G28-1 Lentivirus Second scFv (G28-1)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC119 G28-1 Lentivirus Third scFv (G28-1)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC120 G28-1 Lentivirus Third scFv (G28-1)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-048-3343

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Australia
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