Creative Biolabs provides CellRapeutics™ cytokine release test such as Enzyme-Linked ImmunoSorbent Assay (ELISA) for detecting the secretion of Interferon gamma (IFNγ), Interleukin-2 (IL-2) and other cytokines.
Our ELISA kits are designed to measure a range of different cytokines released by CAR-T cells or CAR-NK cells against tumor .Preclinical studies show that the cytokine release level should be in a reasonable range which can just activate T cells but not cause cytokine storm. Therefore, technically, the IFNγ or IL-2 level in culture medium can reflect the activation degree of CAR-T cells or CAR-NK cells, which can also indicate the survival activity and proliferative capacity of CAR modified immune cells. We guarantee that our premium service can satisfy customers’ special requirements.
JoVE Science Education Database. Basic Methods in Cellular and Molecular Biology. The ELISA Method. Journal of Visualized Experiments, Cambridge, MA, doi: 10.3791/5061 (2014).
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