Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsThe advent of Chimeric Antigen Receptor T-cell (CAR-T) therapies has revolutionized the field of oncology, providing new avenues for treating various forms of cancer. Our 20 years of experience in the biotechnology sector have equipped us with the expertise and technological capabilities to support the entire lifecycle of CAR-T products, from early development to commercialization.
EXPLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsGet a real taste and understanding of the business and culture of one of the world's great research-based cellular and gene therapy discovery and development companies.
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Based on the outstanding expertise and rich experience, Creative Biolabs has specially developed a system approach of TCR generation and optimization for TCR development.
T cell mediated cellular immunity plays a pivotal role in tumor rejection. Through their surface T cell receptor (TCR), T cells recognize short 9-10mer peptide epitope presented by major histocompatibility complex (MHC) class I proteins on the surface of cells. Enhancing the numbers and activity of tumor-infiltrating lymphocytes (TILs), which are mostly composed of T lymphocytes, is among the early approaches that immunologists and oncologists tested to treat cancer. TCRs have been intensively studied for anti-tumor immunotherapy. The idea that targeting single epitopes derived from cancer-specific or cancer-related antigens is sufficient to treat cancer has fueled research efforts to identify suitable epitopes and has opened up many new routes for developing novel anti-cancer immunotherapy agents. Therefore, TCRs with their own advantages become significant products for cancer therapy.
Preclinical in vivo therapeutic efficacy test of TCR-T cells in animal models provides valuable information for their late clinical application. Particularly, efficacy of TCRs is a key factor for selection in clinical later stage. With years of experience in preclinical in vivo research and project management, Creative Biolabs is able to provide therapeutic efficacy test service for a proof-of-concept or therapeutic efficacy validation by utilizing appropriate animal models, designing comprehensive research practices and handling high-quality in vivo studies. We are capable of conducting many tests to evaluate the therapeutic efficacy of the CAR-T cell therapy, such as in vivo imaging, clinical observation.
Creative Biolabs has the capability to enable you to free up your time for core work and project. Our service can be designed to meet your special needs if you have any requirements. If you are interested in our service, please contact us by E-mail and our team will get back to you as soon as possible.
For any technical issues or product/service related questions, please leave your information below. Our team will contact you soon.
All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
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The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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