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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MOREWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MOREUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don’t find the answers you’re looking for, contact us for additional assistance.
EXPLORE MOREInterleukin-13 receptor subunit alpha-2 (IL-13Rα2), also called CD213A2, CT19, IL-13R, IL13BP, is a membrane bound protein that in humans is encoded by the IL13RA2 gene. This protein is a component of the cell surface receptor. Compared to IL-13Rα1, IL-13Rα2 play an opposite role as a potent IL13 antagonist. IL-13Rα2 is infected in the disease of glioblastoma multiforme and malignant glioma though the pathway of immune system and Akt signaling.
Associated Disease
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | Inquiry & Datasheet |
| CAR-T-2-M401-BZ | IL13Rα2 h(41BB-CD3ζ) CAR, [T] | Human | Human | scFv-41BB-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M401-CZ | IL13Rα2 h(b2c-CD3ζ) CAR, [T] | Human | Human | scFv-b2c-CD3ζ | Lentiviral | T cell | ||
| CAR-T-1-M401-2 | IL13Rα2 h(CD28) CAR, [T] | Human | Human | scFv-CD28 | Lentiviral | T cell | ||
| CAR-T-3-M401-2BZ | IL13Rα2 h(CD28-41BB-CD3ζ) CAR, [T] | Human | Human | scFv-CD28-41BB-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M401-2Z | IL13Rα2 h(CD28-CD3ζ) CAR, [T] | Human | Human | scFv-CD28-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M401-2G | IL13Rα2 h(CD28-FcεRIγ) CAR, [T] | Human | Human | scFv-CD28-FcεRIγ | Lentiviral | T cell | ||
| CAR-T-3-M401-2XZ | IL13Rα2 h(CD28-OX40-CD3ζ) CAR, [T] | Human | Human | scFv-CD28-OX40-CD3ζ | Lentiviral | T cell | ||
| CAR-T-1-M401-Z | IL13Rα2 h(CD3ζ) CAR, [T] | Human | Human | scFv-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M401-4Z | IL13Rα2 h(CD4-CD3ζ) CAR, [T] | Human | Human | scFv-CD4-CD3ζ | Lentiviral | T cell | ||
| CAR-T-2-M401-4G | IL13Rα2 h(CD4-FcεRIγ) CAR, [T] | Human | Human | scFv-CD4-FcεRIγ | Lentiviral | T cell | ||
| CAR-T-2-M401-8Z | IL13Rα2 h(CD8-CD3ζ) CAR, [T] | Human | Human | scFv-CD8-CD3ζ | Lentiviral | T cell | ||
| CAR-T-1-M401-G | IL13Rα2 h(FcεRIγ) CAR, [T] | Human | Human | scFv-FcεRIγ | Lentiviral | T cell | ||
| CAR-LC235 | Anti-IL13Rα2 (m47) h(-CD28-CD3ζ) CAR, pCDCAR1 | Human | m47 | Mouse | scFv--CD28-CD3ζ | Retroviral | T cell | |
| CAR-LC236 | Anti-IL13Rα2 (m47) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | m47 | Mouse | scFv-CD28-41BB-CD3ζ | Retroviral | T cell | |
| CAR-LC283 | Anti-IL13Rα2 h(CD3ζ) Ligand-based CAR, pCDCAR1 | Human | Human | IL13-CD3ζ | Retroviral | T cell | ||
| CAR-LC284 | Anti-IL13Rα2 h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 | Human | Human | IL13-CD28-CD3ζ | Retroviral | T cell | ||
| CAR-LC287 | Anti-IL13Rα2 h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 | Human | Human | Protein-41BB-CD3ζ | Lentiviral | T cell | ||
| CAR-MZ148 | Anti-IL13Rα2 (scFv47) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | m47 | Mouse | scFv-41BB-CD3ζ | Retroviral | T cell | |
| CAR-MZ149 | Anti-IL13Rα2 (scFv47) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 | Human | m47 | Mouse | scFv-CD28-OX40-CD3ζ | Retroviral | T cell | |
| CAR-MZ238 | Anti-IL13Rα2, IL13 mutein E13K h(CD28-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein E13K-CD28-CD3ζ | Retroviral | T cell | |||
| CAR-MZ239 | Anti-IL13Rα2, IL13 mutein E13Y h(CD28-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein E13Y-CD28-CD3ζ | Retroviral | T cell | |||
| CAR-MZ240 | Anti-IL13Rα2, IL13 mutein E13K.K105R h(CD28-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein E13K.K105R-CD28-CD3ζ | Retroviral | T cell | |||
| CAR-MZ241 | Anti-IL13Rα2, IL13 mutein E13Y.K105R h(CD28-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein E13Y.K105R-CD28-CD3ζ | Retroviral | T cell | |||
| CAR-ZP075 | Anti-IL13Rα2 (Hu07H2L) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | Hu07H2L | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-ZP076 | Anti-IL13Rα2 (Hu07H2L) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | Hu07H2L | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-ZP077 | Anti-IL13Rα2 (Hu08H2L) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | Hu08H2L | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-ZP078 | Anti-IL13Rα2 (Hu08H2L) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | Hu08H2L | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-YF391 | Anti-IL13Rα2 (IL13 mutein ((E13K)) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein ((E13K) | scFv-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF392 | Anti-IL13Rα2 (IL13 mutein ((E13Y)) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein ((E13Y) | scFv-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF393 | Anti-IL13Rα2 (IL13 mutein ((E13K.K105R)) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein ((E13K.K105R) | scFv-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF394 | Anti-IL13Rα2 (IL13 mutein ((E13Y.K105R)) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein ((E13Y.K105R) | scFv-41BB-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF395 | Anti-IL13Rα2 (IL13 mutein ((E13K)) h(-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein ((E13K) | scFv-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF396 | Anti-IL13Rα2 (IL13 mutein ((E13Y)) h(-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein ((E13Y) | scFv-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF397 | Anti-IL13Rα2 (IL13 mutein ((E13K.K105R)) h(-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein ((E13K.K105R) | scFv-CD3ζ | Lentiviral vector | T Cell | ||
| CAR-YF398 | Anti-IL13Rα2 (IL13 mutein ((E13Y.K105R)) h(-CD3ζ) CAR, pCDCAR1 | Human | IL13 mutein ((E13Y.K105R) | scFv-CD3ζ | Lentiviral vector | T Cell |
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