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Lenti-IL13Rα2 CAR (scFv-28ζ, m47)-VP (VP-CAR-LC707)

The ready-to-use lentiviral particles of Lenti-IL13Rα2 CAR (scFv-28ζ, m47)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (m47)--CD28-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

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Specifications

  • Type of Therapeutics
  • Chimeric Antigen Receptor
  • Target
  • IL13Rα2
  • Expression Cassette
  • scFv (m47)--CD28-CD3ζ
  • Clone
  • m47
  • Promotor
  • EF1a
  • Packaging System
  • Lentivirus
  • Packaging Cell
  • 293T
  • Targeting Diseases
  • Glioblastoma multiforme

Target

  • Introduction
  • The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.
  • Alternative Names
  • CT19; IL-13R; IL13BP; CD213A2

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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